Cefoselis is a fourth generation cephalosporin. It is used extensively in Japan and China in the clinical treatment of various gram positive and gram negative infections. A 2014 study illustrated that Cefoselis is effective at treating respiratory and urinary tract infections. [1]

头孢噻利（INN：Cefoselis）是第四代头孢菌素。在日本和中国临床广泛用于治疗各种革兰氏阳性和革兰氏阴性感染。2014年的一项研究表明，头孢噻利可有效治疗呼吸道和尿路感染。 [1]

Cefoselis is a semisynthetic, broad-spectrum, beta-lactamase-resistant, fourth-generation cephalosporin with antibacterial activity. Cefoselis binds to and inactivates penicillin -binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

头孢噻利是日本藤泽制药有限公司开发的第四代头孢类抗生素，它对革兰氏阳性菌和革兰氏阴性菌均有很好的活性，特别对甲氧西林耐药的金黄色葡萄球菌、绿脓杆菌具有很好的抗菌活性，另外对β-内酰胺酶非常稳定，已在日本等国上市，在临床上得到广泛的应用。 分子量是620.64。

Our results support the clinical development of aztreonam-avibactam, eravacycline, and cefoselis to treat infections caused by Enterobacterales.

Cefoselis, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis penetrates the blood-brain barrier.

头孢噻利(cefoselis，FK037)为第四代头孢菌素，与常用的第三代头孢菌素相比，抗菌谱更广，对产AmpCβ内酰胺酶的肠杆菌科细菌作用增强。 本品较易穿透细菌的细胞外膜，特别是革兰阴性杆菌的细胞外膜，比第三代头孢菌素的穿透性更强，因此有更多的药物进入 ...

Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier.

Cefoselis，一种新型肠道外头孢菌素，对革兰氏阳性和革兰氏阴性需氧的临床菌株具有活性。 体内研究 在正常大鼠中，Cefoselis引起细胞外谷氨酸盐浓度大幅提高。

Cefoselis is a cephalosporin compound having [2- (2-hydroxyethyl)-3-imino-2,3-dihydro-1H-pyrazol-1-yl]methyl and [ (2Z)-2- (2-amino-1,3-thiazol-4-yl)-2- (methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. A 4th generation broad-spectrum cephalosporin.