Our CD16/CD32 monoclonal, recombinant monoclonal and polyclonal antibodies are developed in Rat, Rabbit and Mouse. Find the CD16/CD32 antibody that fits your needs. Choose from 1 of 52 CD16/CD32 antibodies, which have been validated in experiments with 971 publications and 154 images featured in our data gallery.

The 2.4G2 antibody specifically recognizes a common nonpolymorphic epitope on the extracellular domains of the mouse FcγIII (CD16) and FcγII (CD32) Receptors.

Description: The 93 monoclonal antibody reacts with an epitope shared by mouse CD16 and CD32. CD16 (Fc gamma III Receptor) and CD32 (Fc gamma II Receptor) are the low affinity receptors for the mouse IgG Fc portion and are expressed by B cells, monocyte/macrophages, NK cells, and neutrophils.

The 2.4G2 monoclonal antibody reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. CD16 and CD32 are expressed on B cells, monocytes/macrophages, NK cells, …

TruStain FcX™ PLUS is specific to the common epitope of CD16/CD32. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors and is more effective than TruStain FcX™. The antibody was purified by affinity chromatography. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Therefore, Ab93 is referred to as an Anti-CD16/32 or Anti-FcgRII/III antibody. CD16 is variably expressed on neutrophils, macrophages, and natural killer (NK) cells whereas CD32 is expressed on B cells, monocytes, granulocytes, platelets and endothelial cells.

CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD32 (FcγRII) is a 40 kD transmembrane glycoprotein that binds to the Fc region of IgG with low affinity.

在人类免疫系统中，CD16（FcγRIII） 是一种不可或缺的细胞表面抗原，分布在多种免疫细胞上，包括自然杀伤（NK）细胞、 单核细胞 、巨噬细胞和 中性粒细胞 等。 作为免疫球蛋白超家族（IgSF）的成员，CD16可以结合IgG抗体的Fc片段，在免疫应答中发挥多重作用：启动吞噬、激发呼吸爆以及诱导抗体依赖的细胞毒性（ADCC），从而成为抗癌和抗病毒免疫防御中的核心角色。 CD16通过两种基因形式进行表达：FcγRIIIa（CD16a） 和 FcγRIIIb（CD16b）。 主要存在于 …

Rat monoclonal [93] to CD16+CD32 - BSA and Azide free; Suitable for: Flow Cyt, Blocking, ICC/IF; Reacts with: Mouse, Human; Isotype: IgG2a

APC-65057 targets CD16/32 in FC applications and shows reactivity with Mouse samples. PBS with 0.1% sodium azide and 0.5% BSA. Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.