The clinical spectrum of Caspr2 antibody–associated disease
Contactin-associated protein-like 2 (Caspr2) is a membrane protein expressed in the CNS and peripheral nervous system. It is essential for proper localization of voltage-gated potassium …
神经综述：抗接触蛋白相关蛋白-2抗体自身免疫性脑炎研究进展
2020年7月14日 · CASPR2是轴突蛋白IV超家族的一种细胞黏附分子，表达CASPR2的自身抗体可导致一系列与年龄相关的、可治疗的临床综合征，表现为周围神经过度兴奋、边缘性脑炎 …
Systematic review of the clinical spectrum of CASPR2 antibody
We present a case report and performed a systematic review of the literature to summarize: (1) the clinical phenotype of patients with CASPR2 antibodies, (2) the findings in neurological …
全面认识抗接触蛋白相关蛋白2抗体脑炎 - 中华医学杂志
CASPR2是由CNTNAP2基因编码的轴突蛋白超家族中的一种细胞黏附分子，是跨膜蛋白，CASPR2和VGKCs的分布位置相似，都是主要位于与郎飞结相邻的近结旁 …
Investigations of Caspr2, an autoantigen of encephalitis and ...
Three different sets of experiments establish Caspr2 as an autoantigen of these disorders, 1) specific immunostaining of HEK293 cells expressing Caspr2 with serum or CSF of patients, 2) …
The clinical spectrum of Caspr2 antibody-associated disease
2016年8月2日 · Caspr2 antibodies associate with a treatable disorder that predominantly affects elderly men. The resulting syndrome may vary among patients but it usually includes a set of …
神经综述：抗CASPR2抗体相关神经系统疾病的研究进展
2019年1月17日 · 帕金森综合征是以帕金森病临床特征（静止性震颤、运动迟缓、肌强直和姿势平衡障碍）为表现，对左旋多巴反应差和附加临床特征为特征的异质性神经疾病组。 以下附加 …
成年人抗接触蛋白相关蛋白2抗体自身免疫性脑炎的临床特征研究
随着关于自身免疫性脑炎（autoimmune encephalitis，AE）的研究进展，越来越多具有致病性的抗神经细胞抗体被发现，其中抗接触蛋白相关蛋白2（contact protein related protein-2，Caspr …
Systematic review of the clinical spectrum of CASPR2 ... - Springer
2020年1月7日 · Contactin-associated protein-like 2 (CASPR2) autoantibody disease has a variable clinical phenotype. We present a case report and performed a systematic review of …
CASPR2-antibody encephalitis - Autoimmune Encephalitis Alliance
CASPR2 (Anti-contactin-associated protein-like 2) antibody is a neural specific antibody associated with varied autoimmune neurological disorders including autoimmune encephalitis …