What is captopril? Captopril is used in adults alone or in combination with other medications to treat high blood pressure (hypertension) and congestive heart failure.

Captopril is an FDA-approved medication that plays a pivotal role in managing hypertension, left ventricular dysfunction post-myocardial infarction, and diabetic nephropathy. Its therapeutic efficacy primarily stems from inhibiting the renin-angiotensin-aldosterone system (RAAS), making it a cornerstone in treating these cardiovascular conditions.

卡托普利，是一种有机化合物，化学式为C9H15NO3S，主要用作血管紧张素转移酶抑制药，被应用于治疗高血压和某些类型的充血性心力衰竭。 本品为1- [ (2S)-2-甲基-3-巯基-丙酰基]-L-脯氨酸，按干燥品计算，含C9H15NO3S不得少于97.5%。 本品为白色或类白色结晶性粉末，有类似蒜的特臭，味咸。 本品在甲醇、乙醇或三氯甲烷中易溶，在水中溶解。 本品的熔点（通则0612）为104～110℃。 取本品，精密称定，加乙醇溶解并定量稀释制成每1mL中约含20mg的溶液，依 …

卡托普利是一种血管紧张素转化酶抑制剂（ACE inhibitor或ACEI），能够使血管紧张素Ⅰ不能够转化为血管紧张素Ⅱ，从而降低外周血管阻力，还可以通过抑制醛固酮分泌，从而减少水、钠潴留；通过干扰缓激肽的降解来扩张外周血管。

2024年5月30日 · Captopril blocks the angiotensin-converting enzyme (ACE) from forming a hormone called angiotensin II. When angiotensin II binds to receptors, it causes your blood vessels to constrict. Blocking...

2023年6月12日 · Detailed Captopril dosage information for adults. Includes dosages for Hypertension, Congestive Heart Failure, Diabetic Nephropathy and more; plus renal, liver and dialysis adjustments.

2022年9月13日 · Captopril tablets are indicated for the treatment of hypertension. In using captopril tablets, consideration should be given to the risk of neutropenia/agranulocytosis (see WARNINGS). Captopril tablets may be used as initial therapy for patients with normal renal function, in whom the risk is relatively low.

2018年2月22日 · Captopril is used to treat high blood pressure, heart failure, and heart problems after a heart attack. It is also used to treat kidney disease in people with diabetes. Captopril belongs to...

2024年2月28日 · Captopril is an FDA-approved medication that plays a pivotal role in managing hypertension, left ventricular dysfunction post-myocardial infarction, and diabetic nephropathy. Its therapeutic efficacy primarily stems from inhibiting the renin-angiotensin-aldosterone system (RAAS), making it a corners …

2023年4月20日 · Captopril tablets, USP, are a specific competitive inhibitor of angiotensin I-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I to angiotensin II. Captopril is ... Mechanism of Action - The mechanism of action of captopril has not yet been fully elucidated.