肉碱棕榈酰转移酶 1A（CPT1A）基因 | MCE - MCE-生物活性 ...
CPT I 是肉毒碱依赖性线粒体内膜转运中的关键酶，其缺乏会导致脂肪酸 β-氧化速率降低。 已发现该基因编码不同亚型的可变剪接转录物变体。 [RefSeq 提供，2008 年 7 月]
线粒体长链脂肪酸氧化障碍：肉碱棕榈酰转移酶 I 缺乏症（CPT1A
2023年11月14日 · 肉碱棕榈酰转移酶 I (CPT I) 是一种线粒体膜蛋白，可将长链脂肪酰基辅酶 A 分子转化为其相应的酰基肉碱分子。 然后产生的酰基肉碱可转运到线粒体基质中，在那里它们 …
Carnitine palmitoyltransferase I - Wikipedia
Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase I, is a mitochondrial …
CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential
2020年2月1日 · This review focuses on CPT1A, the liver isoform that catalyzes the rate-limiting step of converting acyl-coenzyme As into acyl-carnitines, which can then cross membranes to …
CPT1A Gene - GeneCards | CPT1A Protein | CPT1A Antibody
2025年3月30日 · CPT1A (Carnitine Palmitoyltransferase 1A) is a Protein Coding gene. Diseases associated with CPT1A include Carnitine Palmitoyltransferase I Deficiency and Carnitine …
Cell Death & Disease：曹亚团队揭示CPT1A介导的脂肪酸氧化通过 …
2022年，中南大学湘雅医院等单位的相关研究人员在《Cell Death & Disease》（IF: 8.5）上发表了题为“CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside …
Cpt1a Drives primed-to-naïve pluripotency transition through lipid ...
2024年9月30日 · Cpt1a is the rate-limiting enzyme in transporting activated medium and long-chain fatty acids into mitochondria for β-oxidation, and its expression level directly impacts …
CPT1A gene - MedlinePlus
The CPT1A gene provides instructions for making an enzyme called carnitine palmitoyltransferase 1A, which is found in the liver. This enzyme is essential for fatty acid oxidation, a multistep …
Mitochondrial CPT1A: Insights into structure, function, and basis …
2023年3月23日 · Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-oxidation, and its deficiency or abnormal regulation can result in diseases like …
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)
肉毒碱棕榈酰基转移酶1a（cpt1a），催化长链脂肪酸-coa缀合物的酰基转移到肉碱上，这是线粒体摄取长链脂肪酸类及其随后在线粒体中的β氧化的重要步骤。