Estimates GFR in CKD patients using serum creatinine, cystatin C, or both. The 2021 CKD-EPI equation is now the recommended standard. This version does not include race, as do the 2009 and 2012 CKD-EPI creatinine and creatinine-cystatin C equations. See here for more on our approach to addressing race and bias on MDCalc.

Limited data suggest serum chloride levels associate with mortality in heart failure, chronic kidney disease (CKD), and pulmonary arterial hypertension. Randomized trials have also shown that administration of crystalloid intravenous fluids with lower chloride concentration may have better renal outcomes.

2020年5月6日 · In CKD patients, higher serum chloride associated with a modestly steeper rate of eGFR decline, and may be a useful biomarker to predict CKD progression. Further studies are needed to determine causality.

Low Cl^- was associated with increased mortality and risk of CV events in pre-dialysis CKD patients. Cl^- may be an additional prognostic indicator in CKD.

2020年6月1日 · Lower serum Cl levels are an independent predictor of death and cardiovascular events. The incremental prognostic value of Cl was superior to that of Na in patients with CKD.

2013年11月13日 · CKD-EPI eGFR was compared against 8-hour measured urinary CL CR. Data capture occurred within 48 hours of admission. One hundred and ten patients (n = 110) were enrolled in the study. 63.6% were male, the mean age was 50.9 (16.9) years, 57.3% received invasive mechanical ventilation, and 30% required vasopressor support.

2017年6月2日 · 慢性肾脏病（CKD）是一种系统性的疾病，既往由于研究技术的限制，只能同时关注两个器官之间的相互关系，如肾脏与心脏、肾脏与骨骼。 最近由 Carmine Zoccali 教授等代表欧洲肾脏病协会-欧洲透析移植协会（ERA-EDTA），在 Nature Review Nephrology 上对 CKD 的系统性损害及相关机制进行综述。 • 由于睡眠呼吸暂停、炎症和氧化应激改变大血管和微血管功能，增加 CKD 患者患脑病的风险. • 组学研究的应用有助于深入地开展 CKD 相关病理生理的研 …

特に、CKD患者の血清Cl濃度は代謝性アシドーシス、アニオンギャップの上昇、利尿薬・炭酸水素ナトリウム等の薬剤の使用といったCKD特有の要因に影響されます。 したがって、CKD患者の血清Cl濃度と予後の関係を検証するには、これらの交絡因子を調整しなければなりません。 そこで我々は、2005年から2014年に大阪大学医学部附属病院腎臓内科外来に通院していた2,661例の保存期CKD患者を対象に後方視的コホート研究を行い、血清Cl濃度と予後の関係を検討し …

Valvular calcification, developing either in the mitral or the aortic valve, is highly prevalent in patients suffering from chronic kidney disease (CKD), in whom their presence correlates with higher cardiovascular and all-cause mortality risk. To date, the …

2025年1月30日 · Chronic kidney disease (CKD) is defined by persistent abnormalities of kidney function or structure that have consequences for the health. A progressive decline...