Converting cis peptides into trans configuration. WARNING: The cispeptide plugin identifies all cis peptide bonds. As noted in the introduction, there are cases in which cis peptides do occur in …

1999年11月19日 · In proteins, the partial double bond character of the peptide bond results in two conformations depending on the value of the dihedral angle, ω [C α (1)-C(1)-N(1′)-C α (1′)]: cis …

2023年11月21日 · Cis-peptide bonds are rare in proteins, and building blocks less favorable to the trans-conformer have been considered destabilizing. Although proline tolerates the cis …

Abstract: This paper focuses on cis-/trans-conformational interchanges of amide bonds in cyclic peptides that contain N-unsubstituted amino acids, N-methylated amino acids, and …

2012年1月8日 · The presence of energetically less favourable cis peptides in protein structures has been observed to be strongly associated with its structural integrity and function. Inter …

Checking the peptide configuration. In order to determine the configuration of each peptide bond (cis/trans), the dihedral angle O-C-N-CA is calculated. If the absolute value is above a …

Commonly, the fraction of cis isomer of nonprolyl peptide bonds is considered to be negligible in accordance with literature values of ∼ 0.15% for the fraction of cis isomer per peptide bond 20.

1999年11月19日 · A comparison of cis peptides containing proline and non-proline residues show differences in conformation, location in the secondary structure and in relation to the centre of …

1999年2月12日 · In a non-redundant set of 571 proteins from the Brookhaven Protein Data Base, a total of 43 non-proline cis peptide bonds were identified. Average geometrical parameters of …

2018年12月1日 · Multidimensional magic-angle spinning solid-state NMR experiments are described that permit cis and trans peptide bonds in uniformly 13 C, 15 N-labeled peptides and …