2014年2月17日 · Lnk −/− CD8 + T cells survived longer in response to stimulation with IL-15 and proliferated even in nonlymphopenic hosts. Transfer of Lnk −/− CD8 + T cells together with …

Here, we describe a previously unrecognized function of Lnk in the control of inflammatory CD8(+) T-cell proliferation and in intestinal homeostasis. Mature T cells from newly generated Lnk …

Ang II infusion increased IFN-γ–producing CD8 + T cells in the spleen and kidneys of Lnk–/– mice compared with WT mice. Moreover, IFN-γ deficiency resulted in blunted hypertension in …

2021年6月21日 · lnk 是一种细胞内衔接蛋白，已被证明可以负向调节 t 细胞激活和细胞因子信号传导。 我们假设 LNK 缺陷通过增强 Th1/Tc1 反应促进主动脉夹层形成。 方法：将血管紧张素 …

2014年2月17日 · Lnk−/− CD8 + T cells survived longer in response to stimulation with IL-15 and proliferated even in nonlymphopenic hosts. Transfer of Lnk−/− CD8 + T cells together with WT …

2025年1月16日 · 清华大学祁海教授团队在其新发表的论文“GZMK-expressing CD8+ T cells promote recurrent airway inflammatory diseases”中，发现了慢性复发性气道炎症（如慢性鼻窦 …

2015年3月2日 · Ang II infusion increased IFN-γ-producing CD8+ T cells in the spleen and kidneys of Lnk-/- mice compared with WT mice. Moreover, IFN-γ deficiency resulted in blunted …

The provision of CD8 + T cells to Cd8-/-or Rag1-/-mice led to the restoration of LrNK cell maturation. Furthermore, co-culture with CD8 + T cells induced immature CD27 + LrNK cells …

Here, we describe a previously unrecognized function of Lnk in the control of inflamma-tory CD8+ T-cell proliferation and in intestinal homeostasis. Mature T cells from newly generated …

2014年6月1日 · Transfer of Lnk(-/-) CD8(+) T cells together with wild-type CD4(+) T cells into Rag2-deficient mice recapitulated a sign of villous abnormality. Our results reveal a link …