2018年4月30日 · Here, we show that Lnc-Tim3 is upregulated and negatively correlates with IFN-γ and IL-2 production in tumor-infiltrating CD8 T cells of HCC patients. Lnc-Tim3 plays a …

2021年3月24日 · Through CD8 T cell subsets profiling of lncRNAs, this study found a key lncRNA-Snhg1 with the conserved naive hi -effector lo -memory hi expression pattern in CD8 …

Furthermore, small interfering RNA targeting lncRNA-CD160 can block HBV infection progression. lncRNA-CD160 acts as an immune suppressive factor and is expressed at a high level in …

2025年3月1日 · 研究结论和讨论部分指出，本研究首次揭示了肿瘤来源的细胞外 lncrna hdac2-as2 在 hbv 相关肝癌进展中的重要作用。hdac2-as2 通过抑制 cd8 + t 细胞的抗肿瘤功能，重塑肿 …

2019年5月1日 · In the present research, we proved that the interference of miR-155 induced CD8+T cell apoptosis and decreased the cytolysis activity by up-regulating Tim-3, thereby …

结论 NSCLC 患者肿瘤组织及外周血中LINC01137 表达显著上调；NSCLC 细胞来源的外泌体中LINC01137 通过靶向CD8+T 细胞中miR-22-3p 并抑制其表达，诱导CD8+T 细胞耗竭，促 …

Here, we show that Lnc-Tim3 is upregulated and negatively correlates with IFN-γ and IL-2 production in tumor-in ltrating CD8 T cells of HCC patients. Lnc-Tim3 plays a pivotal role in...

2020年4月15日 · These data suggest that lncRNA-CD160 suppression in CD8 + T cells could significantly inhibit HBV infection compared with lncRNA-CD160-expressing CD8 + T cells, …

2021年3月24日 · Through CD8 T cell subsets profiling of lncRNAs, this study found a key lncRNA-Snhg1 with the conserved naive hi-effector lo-memory hi expression pattern in CD8 T …

2024年5月17日 · However, CD8 T cells will enter a state of reduced proliferation and activation and weakened anti-cancer effects during continuous stimulation of tumor antigens, termed as …