OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200) [5] is a human protein encoded by the CD200 gene. [6] In humans, the CD200 gene is located on …

We show that CD200 is uniformly expressed in chronic lymphocytic leukemia (CLL) and absent in mantle cell lymphoma (MCL). Importantly, expression of CD200 is retained even in those CLLs …

Through this CD200/CD200R signaling pathway, CD200 exerts its immunosuppressive effects by inhibiting natural killer (NK) cell activation, cytotoxic T cell functions, and M1-polarized …

In this review, we focus on the role of CD200 expression in the differential diagnosis of mature B-cell neoplasms and on the prognostic significance of CD200 expression in CLL, where …

CD200 is a transmembrane protein related to the B7 family of costimulatory receptors involved in T-cell signaling and likely plays a role in physiologic immune tolerance. It is normally …

2021年5月12日 · Our data show that the CD200-CD200R pathway restrains activation of CD200R+ lesional macrophages, their production of CCR2 ligands, and monocyte recruitment …

2025年3月30日 · CD200 (CD200 Molecule) is a Protein Coding gene. Diseases associated with CD200 include Hairy Cell Leukemia and Indian Tick Typhus. Among its related pathways are …