Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate.

2014年6月18日 · BUSULFEX® (busulfan) Injection causes severe and prolonged myelosuppression at the recommended dosage. Hematopoietic progenitor cell transplantation is required to prevent potentially fatal...

2022年11月2日 · Busulfex (busulfan) is a cancer (antineoplastic) medication used to treat the symptoms of chronic myelogenous leukemia (a type of blood cancer). Busulfex is not a cure for leukemia. What Are Side Effects of Busulfex? Busulfex may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat ...

2023年11月29日 · Uses of Busulfex: It is used before bone marrow or stem cell transplant. It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Busulfex? If you have an allergy to busulfan …

2016年6月18日 · Busulfex package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

2023年12月14日 · BUSULFEX (busulfan) Injection causes severe and prolonged myelosuppression at the recommended dosage. Hematopoietic progenitor cell transplantation is required to prevent potentially fatal complications of the prolonged myelosuppression [see Warnings and Precautions (5.1)].

2007年5月14日 · BUSULFEX ® (busulfan) Injection is a potent cytotoxic drug that causes profound myelosuppression at the recommended dosage. It should be administered under the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic drugs and the management of patients ...

Busulfan is used as a pretreatment for patients who are undergoing stem cell transplant for chronic myelogenous leukemia (CML). This medication is given by injection into a...

Medscape - Indication-specific dosing for Myleran, Busulfex (busulfan), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost...

2025年2月8日 · Uses for Busulfex. Busulfan injection is used in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for treatment of chronic myelogenous leukemia. Busulfan belongs to the group of medicines known as alkylating agents.