Bile acid malabsorption is a problem in your intestines. It causes chronic, watery diarrhea. Bile acids (bile salts) that aren’t absorbed properly in your small intestine pass to your large intestine (colon) where they trigger diarrhea symptoms. You can treat the symptoms with bile acid sequestrants. What is bile acid malabsorption?

Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. [1] . Diverse bile acids are synthesized in the liver in peroxisomes. [1][2] Bile acids are conjugated with taurine or glycine residues to give anions called bile salts. [1][2]

2024年4月26日 · Here, we provide a bottom-up approach on bile acids, mechanistically explaining their biochemistry, physiology, and pharmacology at canonical and non-canonical receptors.

2023年5月1日 · Bile acids are steroidal acids found in bile. Primary bile acids are steroids produced via the liver, specifically in peroxisomes.

Bile acids include a group of molecular species with similar, but not identical, chemical structures. Surprisingly, they exhibit diverse physical properties and even more divergent biological characteristics.

2024年5月13日 · Bile is a yellowish-green digestive fluid produced by your liver and stored by your gallbladder. It helps your body break down fats in the foods you eat and makes it easier for digestive enzymes to do their job.

2025年3月12日 · Bile Acid Synthesis and Utilization. The end products of cholesterol utilization are the bile acids. Indeed, the synthesis of the bile acids is the major pathway of cholesterol catabolism in mammals.

Bile acids are potent “digestive surfactants” that promote absorption of lipids (including fat-soluble vitamins), acting as emulsifiers (1,2). Bile acids represent the primary pathway for cholesterol catabolism and account for ∼50% of the daily turnover of cholesterol .

2023年3月8日 · Bile acids are steroid acids found predominantly in bile, synthesized in the liver as end products of cholesterol metabolism. They are responsible for fat emulsification, aiding fat digestion and absorption in the small intestine.

bile acid, any of a group of substances derived from cholesterol that play essential roles in the digestion and absorption of dietary fats and fat-soluble vitamins. Bile acids are synthesized in the liver and are secreted into the bile, which is stored in the gallbladder and released into the small intestine during digestion.