Oxidative stress-induced apoptosis in granulosa cells involves …
2017年4月11日 · H2O2 induced an increase in Bax, Bak and Puma, and a decrease in anti-apoptotic molecules such as Bcl-2, Bcl-xL and Mcl-1. Both knockdown of Puma and …
The Role of Plant Bax Inhibitor-1 in Suppressing H2O2-Induced …
2013年1月1日 · Bax inhibitor-1 (BI-1) is a well-conserved protein in plants and animals that serves as the inhibitor of mammalian proapoptotic proteins as well as plant ROS-induced cell death. …
Edaravone protects HT22 neurons from H2O2-induced apoptosis by ... - PubMed
In addition, the levels of reactive oxygen species (ROS) and the expression of Bcl-2, Bax, p-ERK 1/2, p-JNK, and p-P38 proteins in HT22 cells were examined. Results: Exogenous H2O2 …
ROS如何调节细胞凋亡途径 - do-gene.com
2024年10月16日 · ros（活性氧物种）是一类高度反应性的氧化物质，包括超氧阴离子（o2-）、过氧化氢（h2o2）、羟基自由基（·oh）等。 近年来，研究发现ROS参与了细胞凋亡的调节过 …
The role of plant Bax inhibitor-1 in suppressing H2O2-induced cell ...
Bax inhibitor-1 (BI-1) is a well-conserved protein in plants and animals that serves as the inhibitor of mammalian proapoptotic proteins as well as plant ROS-induced cell death. As a target of …
Dissection of Arabidopsis Bax Inhibitor-1 Suppressing Bax–, …
2004年1月1日 · Here, we demonstrate that reactive oxygen species production induced by the ectopic expression of Bax was insensitive to the coexpression of AtBI-1. Similarly, H 2 O 2 – or …
Hydrogen Peroxide-Induced Akt Phosphorylation Regulates Bax …
2023年2月9日 · We demonstrate that PI3K/Akt mediates phosphorylation of the pro-apoptotic Bcl-2 family member Bax. This phosphorylation suppresses apoptosis and promotes cell survival. …
Prolactin protects hippocampal neurons against H2O2-induced ...
2024年11月5日 · Our findings demonstrate that PRL treatment effectively protects primary mouse hippocampal neurons against H 2 O 2 -induced oxidative damage and apoptosis. …
和厚朴酚通过 ROS 产生和线粒体途径改善氧化应激诱导的 c2c12
本研究发现和厚朴酚抑制过氧化氢 (H2O2) 诱导的 DNA 损伤和线粒体功能障碍，同时减少活性氧 (ROS) 的形成。和厚朴酚对 H2O2 诱导的细胞凋亡的抑制作用与 Bcl-2 的上调和 Bax 的下调有 …
Cysteine 62 of Bax Is Critical for Its Conformational Activation and ...
2008年5月5日 · Using the SW480 human colon adenocarcinoma cell line stably expressing Bax fused to GFP, we showed that H 2 O 2 induces Bax conformational change, mitochondrial …