2025年3月30日 · BNIP3 (BCL2 Interacting Protein 3) is a Protein Coding gene. Diseases associated with BNIP3 include Leiomyomatosis and Pancreatic Cancer. Among its related …

2009年2月20日 · BNIP3 (BCL2 and adenovirus E1B 19-kDa-interacting protein 3) and BNIP3-like (BNIP3L), also known as NIX, are proteins with homology to BCL2 in the BH3 domain, which …

2022年4月11日 · Autophagy-mediated mitochondrial degradation plays pivotal roles in both the acquisition and maintenance of pluripotency, but the molecular mechanisms that link …

BNIP3 knockdown altered mitochondrial morphology, and number, and increased mitophagy. Interestingly, BNIP3 deficiency in NP cells reduced glycolytic capacity reflected by lower …

2021年12月20日 · BNIP3L promotes mitophagy either via recruiting autophagosomes to target mitochondria or enhancing the formation of autophagosomes. BNIP3L-mediated mitophagy is …

Bcl-2 nineteen kilodalton interacting protein (BNIP3) is a BH-3 only Bcl-2 family member that its expression levels increase during stress such as hypoxia through hypoxia inducing factor -1 …

2023年8月30日 · BNIP3 has emerged as a promising therapeutic and diagnostic target for BRCA, SARC, KIRC, and LGG, providing new insights into tumour molecular therapies in the clinic.

Recent studies have discovered that Bnip3 regulates mitochondrial dysfunction, mitochondrial fragmentation, mitophagy, cell apoptosis, and the development of lipid disorder diseases via …

2025年2月9日 · The study suggests that BNIP3 may actually allow cell survival either by preventing ATP depletion or by eliminating damaged mitochondria. Bnip3, a hypoxia-inducible …

2015年8月28日 · Bnip3 is a hypoxia-regulated member of the Bcl-2 family of proteins that is implicated in apoptosis, programmed necrosis, autophagy and mitophagy. Mitochondria are …