2025年3月30日 · BIRC5 (Baculoviral IAP Repeat Containing 5) is a Protein Coding gene. Diseases associated with BIRC5 include Adenocarcinoma and Malignant Pleural …

BIRC5 is an immune-related gene that inhibits apoptosis and promotes cell proliferation. It is highly expressed in most tumors and leads to poor prognosis in cancer patients.

BIRC5 is a very promising and well-studied therapeutic target because of its preferential expression in tumor cells of adult individuals. Here we review some of the most relevant …

An inhibitor of apoptosis (IAP) family member, baculoviral IAP repeat containing five (BIRC5) plays an important role in the occurrence and development of tumors. However, the underlying …

2024年12月5日 · BIRC5 is a promising diagnostic and prognostic biomarker in multiple cancers. Its association with immune subtypes suggests a potential role in the tumor immune …

2019年1月1日 · BIRC5, also known as survivin, has been implicated in cell cycle progression and apoptosis avoidance. BIRC5 is highly expressed in embryonic tissues, however very low or …

BIRC5 is an inhibitor of apoptosis (IAP), or programmed cell death, that is selectively overexpressed in common human cancers (Ambrosini et al., 1997). Progression of the cell …

2023年11月19日 · BIRC5, a member of the apoptosis inhibitor (IAP) family, negatively regulates apoptosis or programmed cell death by inhibiting caspase activation. Due to these properties, …

2021年1月11日 · BIRC5 is an immune-related gene that inhibits apoptosis and promotes cell proliferation. It is highly expressed in most tumors and leads to poor prognosis in cancer patients.

2020年2月2日 · High BIRC5 expression was responsible for shorter relapse-free survival, worse overall survival, reduced distant metastasis free survival, and increased risk of metastatic …