Bcl-3 and NFκB p50-p50 Homodimers Act as ... - ScienceDirect
2004年2月27日 · We demonstrate that a predominance of p50-p50 homodimers binding to the IL-2 promoter κB site in tolerant T cells correlated with repression of NFκB-driven transcription. …
Negative Regulation of Toll-Like Receptor Signaling by NF-κB p50 ...
2007年8月3日 · We report the identification of B cell leukemia (Bcl)–3 as an essential negative regulator of TLR signaling. By blocking ubiquitination of p50, a member of the nuclear factor …
癌蛋白 Bcl-3 可以通过从选定的 kappa B 位点去除抑制性 p50 同源 …
癌蛋白 Bcl-3 可以通过从选定的 kappa B 位点去除抑制性 p50 同源二聚体来促进 NF-kappa B 介导的反式激活。 Laboratory of Immunoregulation, National Institute of Allergy and Infectious …
Activation of nuclear factor-kappaB p50 homodimer/Bcl-3
2003年12月1日 · The discrete yet striking NF-kappaB p50 activation in NPC suggests that p50/p50 homodimers may be important factors in the development of NPC and may contribute …
Inhibition of Transcription by B Cell Leukemia 3 (Bcl-3) Protein ...
2014年3月7日 · We employed immobilized peptide array technology to define a region of p50 required for the formation of a Bcl-3·p50 homodimer immunosuppressor complex. Our data …
Mapping the Interaction of B Cell Leukemia 3 (BCL-3) and Nuclear …
2015年6月6日 · Our data show that BCL-3 makes extensive contacts with p50 homodimers and in particular with ankyrin repeats (ANK) 1, 6, and 7, and the N-terminal region of Bcl-3. Using …
Bcl-3 and NFkappaB p50-p50 homodimers act as transcriptional …
2004年2月27日 · We demonstrate that a predominance of p50-p50 homodimers binding to the IL-2 promoter kappaB site in tolerant T cells correlated with repression of NFkappaB-driven …
BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced …
2004年11月26日 · Following its induction, TNFalpha gene transcription is rapidly attenuated, in part due to the accumulation of NF-kappaB p50 homodimers that bind to three kappaB sites in …
B 细胞白血病 3 (Bcl-3) 蛋白对转录的抑制需要与核因子 kappaB (NF-kappaB) p50 …
Bcl-3 is unable to interact with p50 when these amino acids are mutated, rendering it incapable of inhibiting the transcriptional activity of NF-kappaB. Bcl-3 interaction-defective p50 is …
不同于其他I κ B家族,BCL-3是核蛋白,通过与p50及p52形成异源复合物而担任转录激活剂或转录抑制剂。 BCL-3既可与共激活因子相互作用,也可与转录抑制剂相互作用,激活或抑制靶基因的转 …