Autophagy-related protein 101 also known as ATG101 is a protein that in humans is encoded by the C12orf44 gene (chromosome 12 open reading frame 44). [5] Autophagy is the process of …

2025年3月28日 · ATG101 (Autophagy Related 101) is a Protein Coding gene. Diseases associated with ATG101 include Cholangiocarcinoma and Neurodegeneration With Brain Iron …

Here, we identify a novel mammalian Atg13 binding protein, named Atg101. Atg101 shows no homology with other Atg proteins, and is conserved in various eukaryotes, but not in …

2015年6月1日 · The crystal structure of the Atg101–Atg13 complex elucidates the function of Atg101 and sheds light on the molecular mechanisms of autophagy initiation in higher …

2022年10月27日 · We quantified the levels of various cancer hallmarks and identified ATG101 as the major risk factor for overall survival in HCC. A robust ATG101-related gene signature …

2019年4月5日 · Atg101 is an autophagy-related gene identified in worms, flies, mice, and mammals, which encodes a protein that functions in autophagosome formation by associating …

Now, structural and cell biological analysis of Atg101 together with its binding partner Atg13 reveal that Atg101 is required for stabilization of "uncapped" Atg13 in most eukaryotes and also for …

2024年12月10日 · Gene target information for ATG101 - autophagy related 101 (human). Find diseases associated with this biological target and compounds tested against it in bioassay …

Here, we describe the generation and characterization of an Atg101 loss-of-function mutant in Drosophila and report on the roles of Atg101 in maintaining tissue homeostasis in both adult …

2025年2月8日 · ATG101-related signature predicts prognosis and therapeutic option in hepatocellular carcinoma. ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs …