Age-related macular degeneration (AMD) affects the choroid, RPE and outer retinal layers. The condition is divided into non-exudative/dry and exudative/wet. Early detection of exudative AMD is essential to prevent permanent vision loss.

Optical coherence tomography (OCT) technology allows the acquisition of cross-sectional images of the retina with semihistologic resolution. It permits to define the location and nature of the changes in the retina and adjacent structures and objectively evaluates the thickness of the retina and surrounding structures.

OCT allows to identify specific retinal biomarkers associated with visual acuity (VA) at baseline and to provide information about the patient's visual recovery after anti-Vascular Endothelial Growth Factor (anti-VEGF) treatment, to offer an efficient …

年龄相关性黄斑变性（AMD）是一种发病率与年龄增长明显相关的 黄斑区视网膜变性 类疾病。 AMD的确切发病机制不详，目前认为，光损伤、遗传背景、女性、白种人、吸烟等因素为发病的危险因素。 2、诊断要点. 尽管AMD是临床上常见的致盲性眼病，相关的各种研究日新月异，但在临床诊断方面并无明确的，一致性的认识。 文献中所应用的很多诊断标准多适用于流行病学研究和临床科研，并非都适用于日常的临床工作。 在这儿，彭老师提出的诊断要点仅作为临床实践中 …

Age-related macular degeneration (AMD) is an acquired degeneration of the retina that causes significant central visual impairment through a combination of non-neovascular (drusen and retinal pigment epithelium abnormalities), and neovascular derangement (choroidal neovascular membrane formation).

2022年12月16日 · Initial diagnosis and disease activity is imaged with optical coherence tomography (OCT), a tool for evaluating specific morphological retinal and sub retinal changes relevant for visual function...

2020年4月5日 · OCT is a key diagnostic modality in cases of wet ARMD. It helps assess activity in wet ARMD and hence current day practice considers activity on OCT as benchmark for treatment. Activity is represented by well –circumscribed hyporeflective spaces in the inner retina, subretinally and in the sub-RPE space.

2016年11月25日 · Optical coherence tomography (OCT) has become an established diagnostic technology in the clinical management of age-related macular degeneration (AMD). OCT...

2021年7月17日 · Neovascular AMD (nAMD) is responsible for the majority of cases of severe visual loss in eyes with AMD. Optical coherence tomography (OCT) is the most widely used technology for the diagnosis and follow-up of nAMD patients, which is widely used to study and guide the clinical approach, as well as to predict and evaluate treatment response.

OCT-A is a recent imaging technique allowing a non-invasive assessment of the retinal and choroidal microvasculature, providing valuable data for the diagnosis and monitoring of wet AMD. We aim to determine the diagnosis accuracy, describe the morphological features, and assess the clinical activity of MNV in wet AMD using OCT-A.