Apocynin, also known as acetovanillone, is a natural organic compound structurally related to vanillin. It has been isolated from a variety of plant sources and is being studied for its variety of pharmacological properties.

Here we review the therapeutic potential of apocynin, an essentially nontoxic phenolic compound isolated from the medicinal plant Jatropha multifida. Apocynin is a selective inhibitor of the phagocyte NADPH oxidase Nox2 that can be applied orally and is …

Apocynin is a selective NADPH-oxidase inhibitor with an IC 50 of 10 μM. Apocynin improves acute lung inflammation in Carrageenan -induced pleurisy mice model. Apocynin can also be used for cancer research. Apocynin reverses the aging process in mesenchymal stem cells to promote osteogenesis and increases bone mass.

Apocynin is a naturally occurring methoxy-substituted catechol, experimentally used as an inhibitor of NADPH-oxidase. It can decrease the production of superoxide (O2 −) from activated neutrophils and macrophages while the ability of phagocytosis ...

2013年3月1日 · Apocynin is the most employed inhibitor of NADPH oxidase (NOX), a multienzymatic complex capable of catalyzing the one-electron reduction of molecular oxygen to the superoxide anion. Despite controversies about its selectivity, apocynin has been used as one of the most promising drugs in experimenta …

2021年10月18日 · Apocynin is known as a nontoxic herbal compound with anti-inflammatory potential. This review aimed to assess the effects of apocynin in the attenuation of inflammation and identify its mechanism of action based on a narrative review of available evidence.

Apocynin is a naturally occurring methoxy-substituted catechol, experimentally used as an inhibitor of NADPH-oxidase. It can decrease the production of superoxide (O (2) (-)) from activated neutrophils and macrophages while the ability of phagocytosis remains unaffected.

Apocynin是一种天然存在的甲氧基取代的儿茶酚，用作NADPH氧化酶抑制剂。Apocynin防止p47phox的丝氨酸磷酸化，并阻断其与gp91phox的联系，从而钝化NADPH氧化酶的活性。 Apocynin能够降低活化的嗜中性粒细胞和巨噬细胞中超氧化物(O(2)(-))的产生。Apocynin，代谢转 …

Apocynin is an ortho-methoxy-substituted catecholamine and a potent antioxidant that inhibits NOX and scavenges H2 O 2 [136]. In a recent report, apocynin has been demonstrated to suppress platelet aggregation stimulated by collagen [136].

Apocynin is known as a nontoxic herbal compound with anti-inflammatory potential. This review aimed to assess the effects of apocynin in the attenuation of inflammation and identify its mechanism of action based on a narrative review of available evidence.