2025年3月19日 · Anti-seizure medications, which are also called anticonvulsants or anti-epileptic drugs (AEDs), are medications used to prevent seizures for people who have epilepsy. All AEDs are available only by prescription. Epilepsy is a medical condition characterized by a predisposition to recurrent seizures.

一、癫痫（epilepsy）的概念： 所谓癫痫，是指由于各种已知或未知病因，从而导致大脑局部病灶的神经元兴奋性过高，从而产生产生了阵发性、高频性、同步性的异常放电，并且这种异常放电的信号还可以像周围组织扩散，从而引发大脑功能短暂失调的综合征。 ——其本身并不算是一种疾病，而应当理解成一种症状。 并且，不同的癫痫患者会有完全不同的临床表现，所以，根据其临床表现的不同，癫痫有分为许多种类型。 ——特别的，需要明确“ 痫性发作 （seizure）”的概念： …

2024年6月7日 · Modern treatment of seizures started in 1850 with the introduction of bromides, which was based on the theory that epilepsy was caused by an excessive sex drive. In 1910, phenobarbital (PHB), which...

2022年4月2日 · Most people with epilepsy are treated with a single antiepileptic drug (monotherapy) and current guidelines from the National Institute for Health and Care Excellence (NICE) in the United Kingdom for adults and children recommend carbamazepine or lamotrigine as first-line treatment for focal onset seizures and sodium valproate for generalised on...

In this review, we will attempt to introduce the concepts of ion channel and neurotransmitter modulation and, thereafter, group currently used antiepileptic drugs according to their principal mechanisms of action. In the past decade, nine new drugs have been licensed for …

Anti EP was a protest against the Criminal Justice and Public Order Act 1994, which would prohibit raves (described as gatherings where music is played), with "music" being defined as a "succession of repetitive beats." [7] .

NICE: Pharmacological treatment; Antiepileptic drugs and suicidality: an expert consensus statement from the Task Force on Therapeutic Strategies of the ILAE Commission on Neuropsychobiology (2013); Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes (2013) ...

Antiepileptic drug therapy is the mainstay of treatment for most patients with epilepsy. Seizure classification is an important element in designing the treatment plan, since some antiepileptic drugs have different activities against various seizure types.

2018年6月1日 · Antiepileptic drugs (AEDs) exert their pharmacological properties on both epileptic seizures and behaviour through different mechanisms of action.

2015年5月18日 · Identify common misconceptions associated with the practice of maintaining antiepileptic drug levels within laboratory-defined therapeutic ranges. Assess the efficacy, variability, and utility of monitoring antiepileptic drug levels in various settings. Implement appropriate practices to assess antiepileptic drug efficacy clinically.