Amoxapine, sold under the brand name Asendin among others, is a tricyclic antidepressant (TCA). It is the N-demethylated metabolite of loxapine. Amoxapine first received marketing approval in the United States in 1980, approximately 10 to 20 years after most of the other TCAs were introduced in the United States. [6]

2024年6月3日 · Amoxapine is a tricyclic antidepressant that is used to treat symptoms of depression, anxiety, or agitation. Amoxapine may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Amoxapine is used to treat depression. Amoxapine is in a class of medications called tricyclic antidepressants (TCAs). It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. How should this medicine be used? Amoxapine comes as a tablet to take by mouth.

2023年11月18日 · Amoxapine is classified as a second-generation tricyclic dibenzoxazepine antidepressant approved by the U.S. Food and Drug Administration (FDA). This medication is typically prescribed for managing treatment-resistant or persistent depression.

2024年12月18日 · Amoxapine is an antidepressant with a mild sedative component to its action. The mechanism of its clinical action in man is not well understood. In animals, amoxapine reduced the uptake of norepinephrine and serotonin and blocked the response of dopamine receptors to dopamine. Amoxapine is not a monoamine oxidase inhibitor.

2023年6月22日 · Amoxapine (Brand Names: Asendin) is a tricyclic antidepressant used to treat symptoms of depression, anxiety, or agitation. What Are Side Effects of Amoxapine? Amoxapine may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat, mood changes, anxiety, panic attacks, trouble sleeping,

Amoxapine is a tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.

本药为三环类抗抑郁药，与丙米嗪相比，抗抑郁作用相似，但起效快，对心脏毒性低，抗胆碱作用与镇静作用弱。 本药可通过抑制脑内突触前膜对去甲肾上腺素 (NA)的再摄取 (对5-羟色胺的再摄取影响小)，产生较强的抗抑郁与精神兴奋作用。 口服后迅速被吸收。 与洛沙平的化学结构极为相似，并进行类似的羟基化代谢并与葡萄糖醛酸结合，随尿排出。 其t1/2为8h；主要活性代谢物8-羟基阿莫沙平的t1/2为30h，而7-羟基阿莫沙平的t1/2为6.5h。 用于治疗伴有严重淡漠和轻度焦虑的 …

2025年3月1日 · Amoxapine is used to treat the symptoms of depression. It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain. This medicine is a tricyclic antidepressant (TCA).

What is amoxapine used for? Amoxapine is commonly used to treat depression. Amoxapine may also be used for other conditions as determined by your healthcare provider. How does amoxapine...