
ALDH1B1 Gene - GeneCards | AL1B1 Protein | AL1B1 Antibody
2024年12月24日 · ALDH1B1 (Aldehyde Dehydrogenase 1 Family Member B1) is a Protein Coding gene. Diseases associated with ALDH1B1 include Mitochondrial Disease and …
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1
2022年7月4日 · We have discovered selective inhibitors of ALDH1B1, a mitochondrial enzyme that promotes colorectal and pancreatic cancer. We describe bicyclic imidazoliums and …
醛脱氢酶 1 家族成员 B1(ALDH1B1)基因 | MCE
醛脱氢酶是酒精代谢的主要氧化途径中的第二种酶。 该基因在编码序列中不包含内含子。 该基因座的变异可能会影响酒精相关问题的发展。 [RefSeq 提供,2008 年 7 月] This protein …
Nature子刊:结直肠癌治疗新靶点——ALDH1B1 - 健康界
2022年7月11日 · 在这项最新研究中,研究团队开发了一种 aldh1b1 选择性抑制剂——iguana-1, 这是一种胍类和咪唑类小分子化合物,这两种药效团都能靶向 aldh1b1 活性位点并抑制其功 …
ALDH1B1 aldehyde dehydrogenase 1 family member B1
2025年1月4日 · ALDH1B1 metabolizes nitroglycerin and all-trans-retinaldehyde. One of the three human polymorphisms, ALDH1B1*2, is catalytically inactive, likely due to poor NAD(+) …
ALDH1B1 - Wikipedia
Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene. [5][6] This protein belongs to the aldehyde dehydrogenases family of …
Aldehyde dehydrogenase 1B1: a novel immunohistological marker …
2017年9月7日 · We recently reported that ALDH1B1, which has functional roles in tumourigenesis, may be a better CRC marker than ALDH1A1. Human CRC explants and cell …
Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential
2011年2月11日 · ALDH1B1 is a mitochondrial ALDH that metabolizes a wide range of aldehyde substrates including acetaldehyde and products of lipid peroxidation (LPO).
Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell
2021年1月6日 · Taken together, ALDH1B1 confers alterations in the cell morphology, cell cycle progression and gene expression, accompanied by significant changes in the chemosensitivity …
Nature子刊:结直肠癌治疗新靶点——ALDH1B1 - 澎湃新闻
2022年7月11日 · 在这项最新研究中,研究团队开发了一种 aldh1b1 选择性抑制剂——iguana-1,这是一种胍类和咪唑类小分子化合物,这两种药效团都能靶向 aldh1b1 活性位点并抑制其 …