ACC有两种亚型，即ACC1和ACC2。 前者定位于细胞质中，生成的丙二酰-CoA用于脂肪酸合成。 ACC2则定位于线粒体的胞质表面，产物用于抑制肉碱棕榈酰转移酶1（CPT1），以减少脂肪 …

Acetyl-CoA carboxylase (ACC) is a biotin -dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic …

2022年3月18日 · Veprik et al. show that Acetyl-CoA-carboxylase 1 (ACC1), an enzyme that couples glucose metabolism to lipogenesis, is involved in glucagon secretion and regulates S …

ACC1 (acetyl coenzyme A carboxylase 1) is a key enzyme that has been recently found to propagate CD4 + T cell-associated inflammation by mediating de novo fatty acid synthesis; …

Acetyl-CoA carboxylases (ACCs) are enzymes that catalyze the carboxylation of acetyl-CoA to produce malonyl-CoA. In mammals, ACC1 and ACC2 are two members of ACCs. ACC1 …

通过T细胞特异性删除乙酰辅酶A羧化酶1（ACC1），这种酶催化乙酰辅酶A转化为丙二酸辅酶A，后者是长链脂肪酸合成的碳供体，导致了在初始小鼠中CD8+ T细胞的外周持续性和稳态增 …

乙酰辅酶A羧化酶（Acetyl CoA carboxylase）是一种生物素酶，能催化“乙酰辅酶 A+ATP+HCO3-→丙二酸单酰辅酶A+ADP+Pi”的反应。 广泛存在于生物界。 在许多所知的乙酰辅酶A羧化酶 …

乙醯輔酶A羧化酶 （英語： Acetyl-CoA carboxylase）是一種 生物素 依賴的 酵素，專門催化生物體內由 乙醯輔酶A 轉變成 丙二醯輔酶A 的化學反應。 這種酵素可分為3個不同區域，分別是 …

ACC is a biotin-containing Enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, …

乙酰辅酶 A (CoA) 羧化酶 (ACC) 催化乙酰辅酶 A 转化为丙二酰辅酶 A，将碳转化为脂肪酸的从头合成，是细胞脂质代谢的主要调节剂。 哺乳动物编码 ACC 的两种亚型：ACC1 是一种胞质 …