Acetyl-CoA carboxylase (ACC) catalyzes the carboxylation of acetyl-CoA to malonyl-CoA (1). It is the key enzyme in the biosynthesis and oxidation of fatty acids (1). In rodents, the 265 kDa ACC1 (ACCα) form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 (ACCβ) is the main isoform in oxidative tissues (1,2).

5 天之前 · Polyclonal Antibody for studying acetyl-CoA carboxylase 1/acetyl-CoA carboxylase 2. Validated for F, IF, IHC, IP, WB. Highly specific and rigorously validated in-house, Acetyl-CoA Carboxylase Antibody (CST #3662) is ready to ship.

圣克鲁斯生物技术公司提供一系列全面的 ACC 抗体，用于研究乙酰-CoA 羧化酶（ACC）在各种生物过程中的作用。 单克隆 ACC 抗体可用于免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组化 (IHCP)、流式细胞术 (FCM) 和酶联免疫吸附试验 (ELISA)。 乙酰-CoA 羧化酶是脂肪酸代谢中的一种关键酶，在调节脂质合成和能量平衡中发挥着至关重要的作用。 通过将乙酰-CoA 转化为丙二酰-CoA，ACC 可影响脂肪酸的氧化和合成，从而使其成为代谢紊乱、肥胖和心 …

81656-1-RR targets ACC1 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Suitable for: WB, IHC-P; Reacts with: Human; Isotype: IgG; 你可能会感兴趣

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle.

乙酰辅酶A羧化酶(Acetyl-CoA carboxylase,ACC)是一种生物素(biotin)依赖的可以不可逆催化乙酰辅酶A发生羧化反应产生丙二酰辅酶A，在脂肪酸合成途径中起关键作用。

Polyclonal Antibody for studying acetyl-CoA carboxylase 1. Validated for IP, WB. Highly specific and rigorously validated in-house, Acetyl-CoA Carboxylase 1 Antibody (CST #4190) is ready to ship.

乙酰辅酶A羧化酶（ACC）是一个复杂的多功能酶系统，可催化乙酰辅酶A羧化成丙二酰辅酶A，这是脂肪酸合成中的限速步骤。 运动可降低人体肌肉中乙酰辅酶A羧化酶的活性。 ACCα（ACC1）是长链脂肪酸生物合成中的限速酶，而ACCβ（ACC2）可控制线粒体脂肪酸氧化。 ACC的这两种异构体控制细胞中的脂肪酸含量。 ACCα的催化功能受靶向丝氨酸残基的磷酸化（失活）和去磷酸化（激活）以及柠檬酸或棕榈酰辅酶A的别构转化的调节，这是该酶的短期 …