2022年9月12日 · THE CLAIM: Multiple skeptics on social media have claimed the BA.5-specific booster may be unsafe because, before humans began receiving it, it was tested on only eight mice. THE FACTS: The basic fact is actually true — the preliminary findings presented by Pfizer were based on tests in eight mice.

快速老化痴呆模型小鼠SAMP8是SAMP系中的一个亚系，主要以学习、记忆能力障碍为老化特征，是目前公认的比较理想的自然衰老痴呆模型。 此后，除维持兄妹交配外，根据其衰老等级分值、寿命和病理表型进行选择性地繁育，繁育出9个P系即P1、P2、P3、P6、P7、P8、P9、P10和P11，3个R系即R1、R4和R5。 各系小鼠有不同的特征性病理表现。 SAMP8小鼠寿命一般为12-13个月。 统称SAMP和SAMR系为快速老化小鼠。 8月龄时SAMP的老化度评分为7.97， …

2023年9月13日 · Preliminary tests conducted by Pfizer in June 2022 were done on eight mice. The actual number of mice involved in the recent trials is unclear.

2022年9月30日 · After the US approved Pfizer-BioNTech's new bivalent vaccine that targets strains of the Omicron variant, Facebook users claimed it was only tested using "preliminary data from eight mice". But...

2022年8月30日 · They have not released those data publicly, although at the June FDA meeting, Pfizer presented preliminary findings in eight mice given BA.4/BA.5 vaccines as their third dose. Compared with the mice that received the original vaccine as a booster, the animals showed an increased response to all Omicron variants tested: BA.1, BA.2, BA.2.12.1, BA ...

The claim Pfizer only provided data from mice trials in its application to US authorities for its BA.4/5 COVID-19 booster vaccine is misleading. The authorisation was also based on pre-clinical and clinical data for the original mRNA vaccines and a bivalent BA.1 booster vaccine.

2022年9月12日 · Fact check: Were new COVID-19 boosters tested in just 8 mice? Should it matter?

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2022年9月6日 · Right now, there is only final evidence from "8-10 mice" per group." The FDA's website shows for Pfizer the agency also relayed on the final study evidence from "8 mice." But human trials are...