2023年4月17日 · Levodopa is the precursor to dopamine. Most commonly, clinicians use levodopa as a dopamine replacement agent for the treatment of Parkinson disease. It is most effectively used to control bradykinetic symptoms apparent in Parkinson disease.

Levodopa, also known as L-DOPA and sold under many brand names, is a dopaminergic medication which is used in the treatment of Parkinson's disease and certain other conditions like dopamine-responsive dystonia and restless legs syndrome. [3] .

l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants [2] and animals, including humans. Humans, as well as a portion of the other animals that utilize l -DOPA, make it via biosynthesis from the amino acid l -tyrosine.

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L-DOPA (Levodopa) 是一种具有口服活性的神经递质多巴胺的代谢前体。 L-DOPA 可以透过血脑屏障，并在大脑中转化为多巴胺。 L-DOPA 具有抗痛觉过敏作用，并有研究帕金森氏病的潜力。 * Please select Quantity before adding items. • Adv Sci (Weinh). 2024 Aug 19:e2403058. [Abstract] • Int J Biol Macromol. 2024 Aug 26;279 (Pt 1):134952. [Abstract] • Free Radic Biol Med. 2024 May 6:S0891-5849 (24)00437-4. [Abstract]

Levodopa is often viewed as the first-line drug for the management of Parkinson's motor symptoms. Levodopa (in pill form) is absorbed in the blood from the small intestine and travels through the blood to the brain, where it is converted into dopamine.

Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier.

左旋多巴，是一种 有机化合物，化学式为C9H11NO4，是 多巴胺 的 前体药物，本身无药理活性，通过 血脑屏障 进入中枢，经 多巴脱羧酶 作用转化成DA而发挥 药理作用。 改善 肌强直 和运动迟缓效果明显，持续用药对震颤、 流涎 、姿势不稳及 吞咽困难 亦有效。 脑炎 后或合并有 脑动脉硬化 以及 中枢神经系统 的 一氧化碳 与 锰中毒 后的症状性 帕金森综合征 （非药源性 震颤麻痹 综合征）。 可减轻震颤麻痹的症状，改善 肌张力，使肢体活动更趋正常。 对轻、中度病情者效 …

2023年4月17日 · Levodopa is the precursor to dopamine. Most commonly, clinicians use levodopa as a dopamine replacement agent for the treatment of Parkinson disease. It is most effectively used to control bradykinetic symptoms apparent in Parkinson disease.

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