Nitrilium ions – synthesis and applications - RSC Publishing
2017年11月16日 · Nitrilium ions have been well-established in organic chemistry for many decades, but recent developments show them to be far more versatile than hitherto recognized. They are known as stable salts, can be generated in …
Nitrilium ions – synthesis and applications - ScienceDirect
We provide a succinct, but comprehensive review on the synthesis, stability, and reactivity of nitrilium ions as synthons for imines, their use in the synthesis of a large spectrum of heterocycles, and their reactions with transition metal complexes.
Visible Light-Promoted Diazoacetates and Nitriles Generating Nitrilium …
2022年8月2日 · The reaction utilized visible light transformation of diazoacetates to the free carbene that could be trapped by nitriles to generate nitrilium ions, followed by nucleophilic attack on the benzotriazoles and carboxylic acids.
Nitrilium salts. New method for the synthesis of secondary amines
Evidence for Homo-Conjugation between Two Revolving 14π-Electron Systems in 10b-Methyl-10c- [2- (10b,10c-dimethyl-10b,10c-dihydropyrenyl)]-10b,10c-dihydropyrene.
Nitrilium ion trapping as a strategy to access structurally diverse ...
2023年9月9日 · The incorporation of heterobiaryl motifs continues to pose synthetic challenges, which is partially due to the difficulties in effecting late-stage metal-catalyzed cross-couplings. We report a new strategy to form heterobiaryls that is based on trapping nitrilium ions.
Nitrilium ions - synthesis and applications - PubMed
2017年12月13日 · Nitrilium ions have been well-established in organic chemistry for many decades, but recent developments show them to be far more versatile than hitherto recognized. They are known as stable salts, can be generated in …
Nitrilium ion trapping as a strategy to access structurally diverse ...
2023年8月9日 · We report a new strategy to form heterobiaryls that is based on trapping nitrilium ions. The sequence is exemplified using oxadiazole- and oxazole-containing biaryl linkages. NMR analysis and molecular dynamics simulations reveal structural control elements common to each member of the heterobiaryl containing peptide family in this study.
Primary Amine Nucleophilic Addition to Nitrilium
2021年12月13日 · The mechanism of interaction between nitrilium derivatives of closo-dodecaborate anions and ammonia has been proposed. The rate-limiting step of the addition process in the nucleophilic attack of ammonia on the C-atom of nitrilium group which was proved on the base of quantum chemistry calculation.
Nitrilium ions - synthesis and applications. - Semantic Scholar
2017年12月14日 · Nitrilium ions have been well-established in organic chemistry for many decades, but recent developments show them to be far more versatile than hitherto recognized. They are known as stable salts, can be generated in …
report a new strategy to form heterobiaryls that is based on trapping nitrilium ions. The sequence is exemplified using oxadiazole- and oxazole-containing biaryl linkages.
Nitrilium Ions – Synthesis and Applications | Request PDF
2017年11月16日 · We provide a succinct, but comprehensive review on the synthesis, stability, and reactivity of nitrilium ions as synthons for imines, their use in the synthesis of a large spectrum of...
Base-Stabilized Nitrilium Ions as Convenient Imine Synthons
It is based on stabilizing readily available, but thermally labile, N -alkylnitrilium triflates with pyridine or DMAP to moderately air-stable adducts. These base-stabilized imine synthons react conveniently with phosphorus- and nitrogen-based nucleophiles to amidines and phosphaamidines.
An - Wiley Online Library
2021年10月26日 · Reported here is an alternative and scalable cyclization strategy based on NCF 3 -containing synthons for constructing N-CF 3 azoles. The approach involves the N-trifluoromethylation of nitriles followed by a [3+2] cyclization between resulting N-CF 3 nitrilium derivatives and 1,3-dipoles.
IUPAC - nitrilium ions (N04156)
2014年2月24日 · Citation: 'nitrilium ions' in IUPAC Compendium of Chemical Terminology, 3rd ed. International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. https://doi.org/10.1351/goldbook.N04156 RIS BibTex EndNote.
Nitrilium Betaine - an overview | ScienceDirect Topics
A nitrilium betaine is a propargyl–allenyl-type 1,3-dipole with nitrogen as the central atom that undergoes 1,3-dipolar cycloaddition reactions with various double- and triple-bonded dipolarophiles, leading to the formation of different classes such as nitrile ylides, nitrile imides, nitrile oxides, and nitrile sulfides.
cross-couplings.We report a new strategy to form heterobiaryls that is based on trapping nitrilium ions. The sequence is exemplified using oxadiazole- and oxazole-containing biaryl linkages.
Construction of N -Heterocycles via Electrochemically Generated ...
2024年8月9日 · Mechanistic investigations revealed that this reactivity proceeds via a key nitrilium ion, i.e., Ritter intermediate, that is generated from the nucleophilic addition of the nitrile to the carbenium ion. This reaction, now termed the Ritter reaction, has found broad applications in organic synthesis (Scheme 17b).
Ion, nitrilium - Big Chemical Encyclopedia
Ion, nitrilium Friedel-Crafts acylation using nittiles (other than HCN) and HCI is an extension of the Gattermann reaction, and is called the Houben-Hoesch reaction (120—122). These reactions give ketones and are usually appHcable to only activated …
What does NITRILIUM mean? - Definitions.net
Nitrilium. A nitrilium ion is a nitrile that has been protonated, [RCNH]+, or alkylated, [RCNR′]+.
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