A light cascade-enhanced synergistic PTT/PDT/CDT was achieved by Yang et al. using the cyclen-Cu 2+ complexes, where tumor-derived H 2 S reacted with Cu 2+ to generate CuS for PTT and release Ce6 for PDT. The intracellular hypoxic stress was amplified to trigger AQ4N-associated CDT, resulting in a light cascade-enhanced synergistic PTT/PDT/CDT.

2024年5月25日 · The CuS@Rutin demonstrated the dual functionality of PTT and PDT. When subjected to near-infrared laser irradiation, it exhibited potent bactericidal effects against Escherichia coli and Staphylococcus aureus , effectively regulated ROS levels, and modulated the expression of inflammation-related cytokines, thereby alleviating local inflammation.

2017年9月1日 · Photodynamic therapy (PDT) and photothermal therapy (PTT) have been emerging as attractive and promising methods for tumor treatment in clinical approaches. CuS nanoparticles are effective and cost-effective agents for PTT. Recently, it was observed that CuS nanoparticles are also excellence candidates for PDT.

2022年2月15日 · CuS-3 exhibits excellent antibacterial efficiency under 808 nm laser irradiation. It exhibits an extraordinary photothermal conversion efficiency of 41.8%. It generates abundant ROS due to the excellent electron transfer efficiency. The synergistic effect of photothermal therapy (PTT) and photodynamic therapy (PDT).

2020年7月3日 · Excellent anti-tumor effects have been achieved by synergistic PTT/PDT/immunotherapy. The metastasis of tumors was effectively inhibited by the immune response of CpG. Thus, our proposed work...

Photodynamic therapy (PDT) and photothermal therapy (PTT) have been emerging as attractive and promising methods for tumor treatment in clinical approaches. CuS nanoparticles are effective and cost-effective agents for PTT.

这里的目标是探索cus纳米颗粒作为ptt和pdt试剂的杀灭机制。 通过简单的湿化学方法，用两亲性聚合物包被，合成CuS纳米颗粒，并在体外和体内检查其对肺腺癌细胞SPC-A-1的治疗潜力使用鼠类癌症模型。

2023年12月14日 · As a PTT/PDT combination therapeutic platform, CuS@COF nanosheets possess a porous TP-BDT-based COF shell, and it can sufficiently contact oxygen to provide high singlet oxygen (1 O 2) yield under 505 nm laser irradiation. Upon illumination with a 1064 nm laser, CuS@COF nanosheets can effectively convert the photon energy into thermal energy ...

Hollow CuS nanoparticles can achieve photothermal and photodynamic therapy (PDT) in tumor treatment. However, excessive GSH in the tumor cells will consume the reactive oxygen species produced by PDT and reduce the PDT effect.

2019年5月14日 · Herein, a novel Pt-CuS Janus composed of hollow semiconductor CuS and noble metallic Pt was rationally designed and successfully synthesized. The hollow CuS shows a large inner cavity for loading sonosensitizer molecules (tetra- (4-aminophenyl) porphyrin, TAPP) to implement SDT.