OGG1，DNA氧化损伤修复者 - 知乎 - 知乎专栏
Recombinant Human N-Glycosylase/OGG1 是一种DNA修复酶，其作为一种修饰酶, 主要具有DNA糖基化酶活性和脱嘌呤/脱嘧啶（apurinic/apyrimidinic，AP）裂解酶活性两种活性。 N-糖 …
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA …
The codon 326 polymorphism in the hOGG1 gene has been suggested to reduce DNA repair enzyme activity based on in vitro functional analysis. The goal of the present study is to …
8-羟基鸟嘌呤DNA糖苷酶(hOGG1)|ELISA指标 - 知乎 - 知乎专栏
8-羟基鸟嘌呤DNA糖苷酶 （hOGG1）是一种DNA糖基化酶，由 OGG1基因 编码。 它是负责切除 8-氧代鸟嘌呤 （8-oxoG）的主要酶，8-氧代鸟嘌呤是暴露于活性氧（ROS）而产生的诱变碱基 …
Structural Characterization of Human 8-Oxoguanine DNA …
The human 8-oxoguanine DNA glycosylase (hOGG1) protein is responsible for initiating base excision DNA repair of the endogenous mutagen 8-oxoguanine.
sylase,hOGG1)是人体内能特异识别8鄄oxoG 并将其切除修复的酶。hOGG1的修复效率降低和功能缺失是造成辐射或化学致突变而诱发相关癌症的重要因素,hOGG1的寡核苷酸多态性(sing. …
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA ...
The codon 326 polymorphism in the hOGG1 gene has been suggested to reduce DNA repair enzyme activity based on in vitro functional analysis. The goal of the present study is to …
Expression of human 8-oxoguanine DNA glycosylase ( hOGG1 ) in …
Jul 29, 2005 · The human homologue of the yeast DNA repair enzyme, 8-oxoguanine-DNA glycosylase (hOGG1), excises 8-oxoguanine, an oxidative form of the guanine nucleotide. 1 …
Label-Free Sensing of Human 8-Oxoguanine DNA ... - ACS Publications
Jan 24, 2018 · Human 8-oxoguanine DNA glycosylase (hOGG1) plays a significant role in maintaining the genomic integrity of living organisms for its capability of repairing DNA lesions. …
The critical active-site amine of the human 8-oxoguanine DNA ...
Sep 1, 1997 · Results: Here, we report the identification of the active-site amine of the human 8-oxoguanine DNA glycosylase (hOgg1), a human BER superfamily protein that repairs the …
hOGG1基因表观调控异常在非小细胞肺癌中作用及机制研究_百度 …
hogg1是一种dna修复酶，可以从dna切除修复8-羟基鸟嘌呤。 研究表明该基因变异可能会影响个体修复损伤DNA的能力，促进肺癌的发生。 我们前期工作证实hOGG1基因甲基化与非小细胞肺 …