c-Jun, the most extensively studied protein of the activator protein-1 (AP-1) complex, is involved in numerous cell activities, such as proliferation, apoptosis, survival, tumorigenesis and tissue …

Mar 30, 2025 · JUN (Jun Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUN include Breast Cancer and Hematologic Cancer. Among …

The concentrations of c-Jun determine the positive and negative regulation of hARE-induced CAT expression. Interestingly, with a small increase in the concentration, c-Jun can heterodimerize …

Dec 4, 2019 · Here we show that CAR T cells engineered to overexpress the canonical AP-1 factor c-Jun have enhanced expansion potential, increased functional capacity, diminished …

Mar 23, 2021 · Here, we identified c-Jun and JunB as essential for cDC1 fate specification and function.

We show that in fibroblasts, c-Jun is required for progression through the G1 phase of the cell cycle; c-Jun-mediated G1 progression occurs by a mechanism that involves direct …

c-Jun is a major component of the dimeric transcription factor activator protein-1 (AP-1), a paradigm for transcriptional response to extracellular signaling, whose components are basic …

c-Jun, a member of the activation protein 1 (AP-1) family of transcription factors, has been implicated in the regulation of many important biological processes including cell cycle …

Cotranslated c-Jun and c-Fos proteins bind 25 times more efficiently to the AP-1 DNA site as a heterodimer than does the c-Jun homodimer. These experiments suggest that in growth …

C-Jun is the most potent transcriptional activator whereas Fos proteins cannot homodimerise but form heterodimers with Jun proteins [224]. The AP-1 motif in the MMP-9 gene is considered by …