PD-1 and PD-L1 inhibitors - Wikipedia
PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitor anticancer drugs that block the activity of PD-1 and PDL1 immune checkpoint proteins present on the surface of …
一文读懂“抗癌神药”——PD-1抑制剂 - 知乎 - 知乎专栏
PD-1/PD-L1单抗就是分别作用于肿瘤细胞上PD-L1或T细胞上PD-1位点，阻止两者相互结合，激活免疫细胞杀伤肿瘤。 大家可能觉得，这两种药物其实是针对同一免疫通路的两个端点，机制 …
pd-1抑制剂 - 百度百科
尼伏单抗（nivolumab）是一种结合于程序性死亡受体-1（PD-1）的单克隆抗体，通过阻断PD-1及其配体PD-L1和PD-L2间相互作用，从而阻断PD-1通路介导的 免疫抑制 反应，包括抗 肿瘤免 …
PD-1/PD-L1抑制剂 - 维基百科，自由的百科全书
PD-1/PD-L1抑制剂 是一组用于治疗 癌症 的 免疫检查点抑制剂 （英语：Checkpoint inhibitor）。 PD-1 （英语：PD-1） 和 PD-L1 都是存在于细胞表面的蛋白质。 此类的免疫检查点抑制剂正在 …
三分钟读懂PD-1/PD-L1免疫治疗。 - 知乎专栏
2020年7月20日 · 1：人体的 T淋巴细胞 是免疫细胞，能够识别并且杀灭肿瘤细胞； PD-1 是T淋巴细胞的调节蛋白，但是抑制淋巴细胞的免疫杀伤左右，好处是避免T淋巴细胞杀伤了正常的人 …
Immune Checkpoint Inhibitors - NCI - National Cancer Institute
Blocking the binding of PD-L1 to PD-1 with an immune checkpoint inhibitor (anti-PD-L1 or anti-PD-1) allows the T cells to kill tumor cells (right panel). How do immune checkpoint inhibitors …
Anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint …
2023年6月22日 · Compare anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors) (anti-programmed cell death-1 (PD-1) monoclonal antibodies). View important …
PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy
PD1/PDL1 inhibiters unblock the immune suppression of anti-tumor T cells (Figure 1), which results in T cell multiplication and permeation into the TME and inducing an anti-tumor …
Clinical efficacy and safety of anti-PD-1/PD-L1 inhibitors for the ...
2020年2月7日 · Anti-PD-1/PD-L1 inhibitors were identified as a preferable treatment option for advanced or metastatic cancer patients who are male, aged < 65 years, current or former …
PD-1/PD-L1 blockade therapy with atezolizumab: a new ... - Springer
2025年3月26日 · PD-L1, also known as B7-H1, is a ligand of the programmed death receptor 1 (PD-1) encoded by the CD274 gene, localized on 9p24.1 chromosome [].PD-L1 is …