Find the CD25 antibody that fits your needs. Choose from 1 of 238 CD25 antibodies, which have been validated in experiments with 3992 publications and 2004 images featured in our data gallery. ... Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, …

Find the CD25 antibody that fits your needs. Choose from 1 of 239 CD25 antibodies, which have been validated in experiments with 3992 publications and 2005 images featured in our data gallery. ... Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, …

2021年11月25日 · Here we identified two human anti-CD25 antibodies, BA9 and BT942, which did not prevent the activation of IL-2R signaling pathway by IL-2. BT942 had weaker binding and cytotoxic activity to human...

抗CD25克隆7D4是一种非“非耗竭(non-depleting)”性 IgM，可结合小鼠的CD25，但无阻断IL-12信号传导活性。 在该研究中，研究者们通过解析7D4的可变区域并将其克隆到小鼠IgG2a主干中，产生了一种耗竭性、非IL-12阻断性CD25抗体（non-IL-2 blocking antibody，anti-CD25NIB）。

2021年10月2日 · Inhibiting the binding of IL-2 to CD25, anti-CD25 monoclonal antibodies have been first developed as therapeutic agents to treat organ transplant rejection and GVHD (Basilixumab, a Novartis chimeric mouse-human CD25 antibody, 1998 approval) and multiple sclerosis (Daclizumab, a Biogen humanized CD25 antibody, 1997 …

CD25 is a 55 kD type I transmembrane glycoprotein also known as low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4 + T cells termed T regulatory cells.

2021年10月26日 · Camidanlumab Tesirine是由ADC Therapeutics公司研发的一款靶向CD25的抗体偶联药物，由一种靶向结合CD25的单克隆抗体（HuMAX®-TAC）通过连接子与PBD二聚体细胞毒素Tesirine偶联而成。

This study investigates the efficacy of anti-CD25 monoclonal antibody (mAb) as a potential MTX alternative. Participants were divided into two cohorts: a single-dose group (25 mg/day anti-CD25 mAb with MTX) and a double-dose group (50 mg/day anti-CD25 mAb without MTX).

CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses. Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes.

Anti-CD25 antibodies are used in antigen-specific immunodetection in biological samples. The target CD25 is a known alias name of the protein interleukin 2 receptor subunit alpha, encoded by the IL2RA gene in humans.