Anti-CD20 monoclonal antibodies: reviewing a revolution - PMC
In this review, we will discuss the physiology of CD20 and its attractiveness as a therapeutic target, as well as the pharmacology, pre-clinical and clinical data for the major anti-CD20 …
靶点常青树：CD20 - 知乎 - 知乎专栏
目前以cd20为靶点的单抗主要分为三代： 第一代就是以强悍疗效而经久不衰的利妥昔及其类似药； 第二代则经过改良的人源化的CD20单抗，但由于其适应症的局限性和抗体结合亲和力的下 …
Next-generation anti-CD20 monoclonal antibodies in …
Understanding how newer anti-CD20 mAbs compare with rituximab in terms of efficacy, safety, convenience, and cost is important for guiding future management of anti-CD20 mAb therapy …
The regulation and function of CD20: an “enigma” of B-cell …
Anti-CD20 monoclonal antibodies act through several mechanisms, including complement-dependent cytotoxicity (CDC), complement-dependent cellular cytotoxicity (CDCC), antibody …
Anti-CD20 treatment for B-cell malignancies: current status
Of the novel anti-CD20 antibodies, only obinutuzumab has shown consistently improved efficacy over rituximab in randomized pivotal trials in indolent non-Hodgkin lymphoma and chronic …
Seronegative Spondyloarthritis as a Complication of Anti-CD20 ...
2 天之前 · Ocrelizumab and ofatumumab are anti-CD20 mAbs with high efficacy in the treatment of MS (Hauser et al., 2017, Hauser et al., 2020). Their use has become widespread since FDA …
The Evolution of Anti-CD20 Treatment for Multiple Sclerosis
3 天之前 · B-cell depletion with CD20-targeted agents is commonly used for treatment of multiple sclerosis (MS), other autoimmune diseases, and certain hematologic malignancies. Initial …
CD20免疫学研究重要靶点-CD20功能指南-赛默飞 | Thermo Fisher …
CD20抗体选择与优化. 抗体选择：选择高特异性、高灵敏度的抗体是关键。 赛默飞解决方案： 提供多种荧光标记的CD20抗体，适用于不同的实验需求。 货号 12-0209-42：Anti-Human …
Phase I/II Study of Adaptive Manufactured Lentiviral Anti-CD20/Anti ...
6 天之前 · To improve outcomes from single targeted CD19 chimeric antigen receptor (CAR) T cells, we used dual targeted lentiviral anti-CD20/anti-CD19 (LV20.19) CAR T cells as part of a …
Anti-CD20 Antibodies | Invitrogen - 赛默飞世尔科技公司
Antibodies that detect CD20 can be used in several scientific applications, including Immunohistochemistry, Flow Cytometry, Western Blot, Immunocytochemistry and ELISA. …