2023年6月8日 · Acute graft-versus-host disease (GVHD) is a common immune complication that can occur after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a...

2023年11月28日 · Acute graft-versus-host disease (aGVHD) remains the major cause of early morbidity and nonrelapse mortality (NRM) after allogeneic hematopoietic stem cell transplantation (HCT) 1.

Haematopoietic stem cell transplantation (HSCT) is central to the management of many haematological disorders. A frequent complication of HSCT is acute graft-versus-host disease (GVHD), a condition in which immune cells from the donor attack healthy recipient tissues.

本文介绍2例agvhd的临床诊断和治疗思路，阐述笔者对agvhd处理的以下观点：①减少agvhd发生重在预防；②鉴别诊断是关键；③要重视agvhd治疗的规范化；④疗效的动态评估能够有效提高复杂情况下的整体疗效。

2023年8月3日 · Acute gastrointestinal graft versus host disease (GI-GVHD) is a common complication following allogeneic haematopoietic cell transplantation (HCT), and is characterised by...

Objective: To compare the chest CT patterns of acute graft-versus-host disease (aGVHD) and infections within 100 days after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in pediatric recipients to help hematologist make definitive diagnosis as early as possible.

GVHD is conventionally split into two main clinical forms: the acute form (aGVHD), when symptoms begin within the first 100 days after the transplant procedure, and the chronic form (cGVHD), when symptoms begin after day 100 [1,2,3]. However, the emergence of broader strategies of HSCT (e.g., non-myeloablative conditioning, in vivo T-cell ...

5 天之前 · To investigate the impact of stem cell infusion timing on aGVHD, we utilized an MHC-mismatched allo-HSCT mouse model in which bone marrow cells and splenocytes were transplanted from BALB/c (H2k d) mice into lethally irradiated C57BL/6J (H2k b) recipients (i.e., BALB/c→C57BL/6J) at either zeitgeber time 5 (i.e., ZT5; 5 h after light onset in a 12–12 h light-to-dark environment) or ZT14 (2 ...

2020年11月3日 · rectal biopsy: necrosis, mucosal ulcerations, crypt dropout (relatively specific in aGVHD) CT abdomen: luminal dilation with thickening of small bowel wall (“ribbon sign”), air fluid levels suggestive of an ileus in aGVHD

Acute graft versus host disease (aGVHD) remains the second leading cause of death following allogeneic hematopoietic stem cell transplant (AHSCT). Over the last five years, the progress in understanding the pathophysiology of this immune based-process helped redefine graft versus host reaction and o …