2013年9月5日 · Previous locomotor activity experiments in mice determined that the sigma receptor ligand YZ-185 (N -phenylpropyl- N ′- (3-methoxyphenethyl)piperazine) enhanced …

Previous locomotor activity experiments in mice determined that the sigma receptor ligand YZ-185 (N-phenylpropyl-N -(3-methoxyphen-ethyl)piperazine) enhanced cocaine-induced hyperactivity …

2013年9月1日 · YZ-067 was more effective than Nahas-3h to decrease cocaine’s effects. YZ-185 both inhibited and enhanced cocaine hyperactivity. The present study examined N …

2016年11月1日 · This study examined the effect of the N -phenylpropyl- N′-substituted piperazine ligands SA4503 (3.4-dimethoxyphenethyl), YZ-067 (4-methoxyphenethyl), YZ-185 (3 …

This study examined the effect of the N-phenylpropyl-N'-substituted piperazine ligands SA4503 (3.4-dimethoxyphenethyl), YZ-067 (4-methoxyphenethyl), YZ-185 (3-methoxyphenethyl) and …

2013年9月5日 · Previous locomotor activity experiments in mice determined that the sigma receptor ligand YZ-185 (N-phenylpropyl-N'- (3-methoxyphenethyl)piperazine) enhanced …

Overall, these results suggest that YZ-185 is a sigma receptor antagonist at the 31.6 μ mol/kg dose and demonstrate that sigma receptors can mediate the development of the conditioned …

YZ-185 (N-phenylpropyl-N -(3-methoxyphenethyl)pip-erazine), a structural congener to SA4503 in that it only lacks the 4-methoxy group on the phenethyl moiety, binds with high afinity...

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2013年9月5日 · It is possible that YZ-185 functions as a sigma receptor antagonist at the higher dose and an agonist at the lower dose; demonstrating the characteristic mixed …