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Whole-sporozoite malaria vaccines: where we are, where we are …
2024年9月16日 · Whole-sporozoite (WSpz) malaria vaccines rely on the administration of Plasmodium sporozoites, the liver-infective forms of malaria parasites, as immunization …
A new malaria vaccination tool based on replication-competent
2024年3月21日 · Vaccination with whole Plasmodium sporozoites potentially represents a significant stride relative to currently available vaccines. Whole-sporozoite (WSpz) …
105.1 WAVA - WSPZ - AM 1260 - Washington, DC - Listen Online
105.1 WAVA - WSPZ is a broadcast radio station in Bethesda, Marilyn, United States, providing Sports Talk, News, and Live Shows as part of the...
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The effect of dosage on the protective efficacy of whole …
2023年11月24日 · Malaria, caused by protozoan parasites of the genus Plasmodium, is the most prevalent parasitic infection worldwide, accounting for ~600,000 of a total of ~725,000 yearly …
2024年9月16日 · Achievements, challenges, and the path forward for WSpz malaria vaccination Over the last ~15 years, the field of WSpz vaccination underwent significant progress, …
The effect of dosage on the protective efficacy of whole …
2023年11月24日 · Immunization with Plasmodium sporozoites, either attenuated or administered under the cover of an antimalarial drug, can induce strong protection against malaria in pre …
里斯本大学最新研究：剂量对全子孢子制剂抗疟疾免疫保护效力的 …
该研究使用小鼠疟疾模型，分析了四种不同的WSpz配方对免疫剂量的保护效力。这些配方包括：（i）早期肝脏阻滞遗传削弱寄生虫（EA-GAP）；（ii）放射性削弱孢子体（RAS）；（iii） …
recognition of a wider and more diverse antigenic repertoire by the host’s immune system. Specifically, immunization of mice with a P. yoelii (Py) LA-GAP has been shown to elicit …