汉黄芩素，又名5,7-二羟基-8-甲氧基-2-苯基-4H-1-苯并呋喃-4-酮，是一种溶于有机溶剂而不溶于水的黄色针状结晶物。 性状：黄色针状结晶（乙醇水溶液或 醋酸乙酯 -苯）。 熔点：203°C. 溶解性：极易溶于甲醇、乙醇、丙酮和醋酸乙酯, 溶于乙醇、醋酸和氯仿, 微溶于苯和水, 不溶于 二硫化碳 和石油英。 Uvλ（EtOHmax nm）（logε）: 249（4.65）, 320 （4.04）。 IRγKBrmax cm-1: 3120（OH）, 1660（CO）, 1614, 1585, 1515, 1500sh（芳环C=C）。

Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis. [2] The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from Oroxylum indicum. [3] It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement.

汉黄芩素 （英語： Wogonin，也称为 5,7-二羟基-8-甲氧基黄酮，5,7-Dihydroxy-8-methoxyflavone）是一种 天然 的O- 甲基化 黄酮类化合物，存在于 黄芩 （学名： Scutellaria baicalensis）等植物中 [2]。 汉黄芩素可作为 糖苷配基 与 糖 形成 糖苷，其形成的糖苷被称为“汉黄芩素苷”（wogonoside），例子有 汉黄芩苷 （汉黄芩素与 葡萄糖醛酸 形成）等 [3]。

Wogonin is a dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8. It has a role as a cyclooxygenase 2 inhibitor, an antineoplastic agent, an angiogenesis inhibitor and a plant metabolite.

Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects. Wogonin (0-200 μM) exhibits a dose- and time- dependent reduces in cell viability of caco-2, SW1116 and HCT116 cells. Wogonin (10-40 μM) induces G1 phase arrest in HCT-116 cells.

汉黄芩素(Wogonin)，一种从传统中药黄芩(Scutellaria Baicalensis)中提取的黄酮类化合物，近年来因其多种生物活性而成为药理学研究的热点。其主要药理作用包括抗炎、抗氧化、抗肿瘤、神经保护、抗病毒及免疫调节等。体外和体内研究表明，汉黄芩素能够通过多种 ...

Wogonin is a prospective candidate to be used in synergism with currently available anticancer medications since it has the ability to reverse cancer cells’ drug resistance. Future scientists and researchers can learn everything about wogonin’s cancer medication targets and how it affects much significant cancer hallmarks.

The roots of this plant contain bioactive compounds, such as wogonin (WOG), wogonoside, baicalein, and baicalin. The aim of this article is to evaluate the therapeutic potential and mechanisms of action of WOG against different cancers.

2020年11月9日 · Wogonin is a medicinal plant-derived flavonoid that has a variety of pharmacological effects, acting as an inhibitor of inflammation mediators produced by macrophages, lymphocytes, microglia, and endothelial cells. Wogonin also serves as ROS scavenger, neuroprotector, anti-allergy, anxiolytics, and anticonvulsant.

2024年5月2日 · Wogonin is a natural flavone compound from the plant Scutellaria baicalensis, which has a variety of pharmacological activities such as anti-cancer, anti-virus, anti-inflammatory, and immune...