2003年4月28日 · WNT10A encodes a peptide containing two N-linked glycosylation sites and residues conserved among WNTs. The protein contains two domains, a signal peptide and the …

2025年3月30日 · WNT10A (Wnt Family Member 10A) is a Protein Coding gene. Diseases associated with WNT10A include Schopf-Schulz-Passarge Syndrome and …

Wnt-10a is a protein that in humans is encoded by the WNT10A gene. [5][6][7] The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These …

WNT10A gene mutations account for about 5 percent of all cases of hypohidrotic ectodermal dysplasia. Most of the WNT10A gene mutations associated with hypohidrotic ectodermal …

2017年6月7日 · Nature Communications - Human WNT10A mutations are associated with dental defects and adult onset ectodermal dysplasia. Xuet al. show that WNT10A-activated ß-catenin …

WNT10A variants deemed pathogenic for TA likely affect protein folding and/or stabilization, leading to decreased WNT signaling and concomitant dysregulated expression of relevant …

2025年3月1日 · Human wingless-type MMTV integration site family member 10A (WNT10A) is a secreted glycoprotein that is involved in signaling pathways essential to ectodermal …

该基因是 Wnt 基因家族的成员。 它在早幼粒细胞白血病和伯基特淋巴瘤的细胞系中强烈表达。 此外，它和另一个家族成员 WNT6 基因在结直肠癌细胞系中强烈共表达。 基因过表达可能通过 …

In this review, we detail how WNT10A is implicated as a key physiological and pathological contributor to syndromic and nonsyndromic disorders, as well as population variants, affecting …

Wnt10a是WNT家族的成员，虽然这种基因的缺乏引起了与牙齿、头发、指甲和皮肤有关的症状，但我们最近证实了涉及骨骼和脂肪的Wnt10a敲除（KO）小鼠的新表型。