Interaction between Wnt/β-catenin and RAS-ERK pathways and …
2018年2月20日 · Aberrant activation of the Wnt/β-catenin and RAS-extracellular signal-regulated kinase (ERK) pathways play important roles in the tumorigenesis of many different types of …
β-catenin Activates ERK: Two Pathways for the Price of One
2007年5月15日 · Wnt/β-catenin signaling stimulates extracellular signal-regulated kinase (ERK) pathways through effects on Ras.
Wnt/β-catenin通路的激活途径及其相关调控在肿瘤研究的应用
2023年11月10日 · Wnt 家族会与 Ras/Raf/MEK/ERK，TGFβ/Smad 等通路产生 Crosstalk，相互影响协作调控与细胞侵袭转移相关的基因，共同参与调解肿瘤细胞 EMT 过程。 还有 许多蛋白 …
Wnt signaling pathways in biology and disease: mechanisms and ...
4 天之前 · The Wnt signaling pathway is critically involved in orchestrating cellular functions such as proliferation, migration, survival, and cell fate determination during development. Given its …
Wnt /β-catenin与RAS-ERK途径之间的相互作用以及通过靶向Wnt …
Wnt /β-catenin和RAS细胞外信号调节激酶（ERK）通路的异常激活在许多不同类型的癌症（尤其是结直肠癌（CRC））的肿瘤发生中起重要作用。 这两种途径的基因，如腺瘤性息肉 …
Interaction between Wnt/β-catenin and RAS-ERK pathways and …
2018年2月20日 · Aberrant activation of the Wnt/β-catenin and RAS-extracellular signal-regulated kinase (ERK) pathways play important roles in the tumorigenesis of many different types of …
Wnt-Dependent Activation of ERK Mediates Repression of …
2021年6月27日 · We show a distinct requirement of ERK signaling in cell fate specification during early calvarial development, and demonstrate cross-talk between Wnt signaling and ERK …
A Theoretical Model of the Wnt Signaling Pathway in the Epithelial ...
This work presents a simple mathematical model of EMT, specifically the roles played by four key proteins in the Wnt signaling pathway: Dishevelled (Dvl), E-cadherin, β-catenin, and Slug.
Interaction of the Wnt/β-catenin and RAS-ERK pathways involving …
2018年5月1日 · In this review, we summarized the current understanding of cross-talk between Wnt/β-catenin and RAS/ERK pathways related with the synergism in the pathogenesis of CRC …
Wnt signaling in cancer: from biomarkers to targeted therapies …
6 天之前 · Wnt signaling pathways are essential for various biological functions, including tissue homeostasis maintenance and embryonic development [1, 2].Disruption of these pathways …