Sequencing of Bacterial Genomes: Principles and Insights into ...
The advent of genome sequencing coupled with advances in bioinformatic analysis to model genome data, promises invaluable insights into bacterial pathogens, including, their evolution, ecology, pathogenesis, and the design of related therapeutic interventions.
A step-by-step beginner's protocol for whole genome sequencing …
2019年3月15日 · Bacterial whole genome sequencing (WGS) is becoming a widely-used technique in research, clinical diagnostic, and public health laboratories. It enables high resolution characterization of bacterial pathogens in terms of properties that include antibiotic resistance, molecular epidemiology, and viru …
Whole-Genome Sequencing of Bacterial Pathogens: the Future …
Recently, whole-genome sequencing (WGS) of pathogens has become more accessible and affordable as a tool for genotyping. Analysis of the entire pathogen genome via WGS could provide unprecedented resolution in discriminating even highly related lineages of bacteria and revolutionize outbreak analysis in hospitals.
Microbial Whole-Genome Sequencing | Bacterial and viral
Microbial whole-genome resequencing involves sequencing the entire genome of a bacteria, virus, or other microbe, and comparing the sequence to that of a known reference. Generating rapid and accurate microbial reference genome sequence information is critical for detecting low frequency mutations, finding key deletions and insertions, and ...
Typing methods based on whole genome sequencing data
2020年2月18日 · Whole genome sequencing (WGS) of foodborne pathogens has become an effective method for investigating the information contained in the genome sequence of bacterial pathogens. In addition, its highly discriminative power enables the comparison of genetic relatedness between bacteria even on a sub-species level.
Whole genome sequencing of bacterial genomes - Coursera
This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector.
Interpreting Whole-Genome Sequence Analyses of Foodborne Bacteria …
Whole-genome sequence (WGS) analysis has revolutionized the food safety industry by enabling high-resolution typing of foodborne bacteria. Higher resolving power allows investigators to identify origins of contamination during illness outbreaks and …
Whole-Genome Sequencing of Bacterial Pathogens: the Future …
2017年8月30日 · Recently, whole-genome sequencing (WGS) of pathogens has become more accessible and affordable as a tool for genotyping. Analysis of the entire pathogen genome via WGS could provide unprecedented resolution in discriminating even highly related lineages of bacteria and revolutionize outbreak analysis in hospitals.
Twenty years of bacterial genome sequencing - Nature
2015年11月9日 · In this Timeline, we review the first two decades of bacterial genome sequencing, which have been marked by three revolutions: whole-genome shotgun sequencing, high-throughput...
Whole genome sequencing options for bacterial strain typing …
2018年4月1日 · Whole genome sequence (WGS)-based strain typing finds increasing use in the epidemiologic analysis of bacterial pathogens in both public health as well as more localized infection control settings.