
von Willebrand factor - Wikipedia
Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion.
Von Willebrand disease - Symptoms & causes - Mayo Clinic
2021年10月26日 · Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn't clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn't perform as it should.
Physiology, Von Willebrand Factor - StatPearls - NCBI Bookshelf
2023年2月20日 · Von Willebrand factor (vWF) is a glycoprotein crucial to primary hemostasis through platelet and subendothelial collagen adhesion and the intrinsic coagulation cascade through factor VIII stabilization.
Von Willebrand disease - Diagnosis & treatment - Mayo Clinic
2021年10月26日 · Von Willebrand factor multimers. This evaluates the structure of von Willebrand factor in your blood, its protein complexes and how its molecules break down. This information helps identify the type of von Willebrand disease you have.
About von Willebrand Disease | Von Willebrand Disease (VWD)
Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that help the blood clot when needed. One of these proteins is called von Willebrand factor (VWF). People with VWD either have a low level of VWF in their blood or the VWF protein doesn't work the way it should.
Von Willebrand Factor: Definition, Function, and Testing - Healthline
2024年8月1日 · Von Willebrand factor (VWF) is a protein crucial to the blood clotting process. If you don’t have enough of this protein, or if it doesn’t work as it’s supposed to, you may have von...
Von Willebrand Disease - StatPearls - NCBI Bookshelf
2023年8月28日 · Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people may complain of excessive bruising, prolonged bleeding from mucosal …
von Willebrand Factor - StatPearls - NCBI Bookshelf
2024年6月28日 · Von Willebrand factor (vWF) mediates platelet adhesion to exposed subendothelial collagen at sites of vascular injury, facilitating the formation of primary hemostatic plugs. Von Willebrand disease (vWD), a bleeding disorder, arises from quantitative or qualitative defects in vWF.
Von Willebrand Disease - Hematology and Oncology - Merck …
Von Willebrand disease (VWD) is a hereditary quantitative deficiency or functional abnormality of von Willebrand factor, which causes platelet dysfunction. Bleeding tendency is usually mild. Screening tests usually show a normal platelet count and, possibly, a slightly prolonged partial thromboplastin time (PTT).
Von Willebrand Factor: Structure and Function
Von Willebrand factor (vWF) is an adhesive, multimeric glycoprotein present in plasma, platelets, and subendothelium, which has two main functions: (1) it serves as a carrier for factor VIII and (2) it plays a crucial role in platelet adhesion to subendothelium, acting as a “bridge” between platelet membrane glycoprotein (GP) Ib and GP IIb ...