2025年2月6日 · Here, long-range regulation by VirB, a transcriptional regulator that alleviates H-NS-mediated silencing of key virulence genes in Shigella species, is explored in vivo to test …

VirB is a key transcriptional regulator of genes found on the large virulence plasmid (pINV) (6, 7) which directly or indirectly leads to the upregulation of about 50 genes (7 – 9), including those …

2023年11月25日 · VirB is a transcriptional activator of virulence in the gram-negative bacterium Shigella flexneri encoded by the large invasion plasmid, pINV. It counteracts the transcriptional …

2024年1月5日 · Thus, VirB represents a CTP-dependent molecular switch that uses a loading-and-sliding mechanism to control transcription during bacterial pathogenesis. Shigella species …

VirB is a key regulator of genes located on the large virulence plasmid (pINV) in the bacterial pathogen Shigella flexneri. VirB is unusual, as it is not related to other transcriptional …

VirB is a key transcriptional regulator of genes found on the large virulence plasmid (pINV) (6, 7) which directly or indirectly leads to the upregulation of about 50 genes (7 – 9), including those …

2021年6月1日 · Our findings: 1) provide novel insight into VirB:pINV interactions, 2) suggest that VirB may have utility as a DNA marker, and 3) raise questions about how and why this anti …

2023年5月18日 · The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without a functional virB gene, Shigella cells …

2023年5月18日 · On the virulence plasmid, VirB functions to offset transcriptional silencing mediated by the nucleoid structuring protein, H-NS, which binds and sequesters AT-rich DNA, …

During genetic transformation of plant cells by Agrobacterium tumefaciens, 11 VirB proteins and VirD4 are proposed to form a transmembrane bridge to transfer a DNA-protein complex (T …