Ubiquitin-specific-processing protease 7 (USP7), also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP), is an enzyme that …

USP7 controls cellular levels of several key proteins involved in DNA damage response. The enzyme has been extensively studied due to its ability to regulate the level of tumor …

In this mini-review we focus on the de-ubiquitinating enzyme USP7, and summarize latest advances in understanding its structure, substrate specificity and relevance to human cancers.

Mar 30, 2025 · USP7 (Ubiquitin Specific Peptidase 7) is a Protein Coding gene. Diseases associated with USP7 include Hao-Fountain Syndrome and Autism Spectrum Disorder. …

Jan 16, 2018 · USP7-related diseases are caused by changes (mutations) in a protein-coding gene called USP7. The clinical features in affected children include developmental …

Ubiquitin-specific protease 7 (USP7) is one of the most extensively studied deubiquitinases. USP7 exhibits a high expression signature in various malignant tumors, and increased USP7 …

USP7 is a cysteine protease consisting of a TRAF region, catalytic region, and C-terminal ubiquitin-like (UBL) region, and it interacts with tumor suppressors, transcription factors, and …

USP7 plays a role in the pathogenesis of multiple myeloma, and high expression of USP7 is a poor prognostic marker for MM patients. findings suggest that USP7 acts as a negative …

Ubiquitin-Specific Peptidase 7 (USP7), or herpes virus-associated protease (HAUSP), is the largest family of the deubiquitinating enzymes (DUBs). Recent studies have shown that USP7 …

Mar 10, 2025 · The Wistar Institute's Paul M. Lieberman, Ph.D. and lab identified and tested a new method for targeting certain cancers caused by Epstein-Barr Virus (EBV), in the paper, …