USP7 - Wikipedia
Ubiquitin-specific-processing protease 7 (USP7), also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP), is an enzyme that …
USP7是一种对DNA复制至关重要的SUMO去泛素酶 - 知乎
研究结论：usp7是哺乳动物dna复制所必需的sdub，并确定usp7是维持复制叉周围富含sumo的环境所需的第一个因素。 结论与讨论 综上所述，作者发现USP7是一个与复制体相关的DUB， …
USP7 Gene - GeneCards | UBP7 Protein | UBP7 Antibody
2024年12月25日 · USP7 (Ubiquitin Specific Peptidase 7) is a Protein Coding gene. Diseases associated with USP7 include Hao-Fountain Syndrome and Autism Spectrum Disorder. …
USP7: structure, substrate specificity, and inhibition - PMC
USP7 is involved in regulation of the nucleotide excision repair (NER) pathway. Specifically, it prevents degradation of the XPC protein that recognizes helix-distorting DNA lesions and …
USP7: Structure, substrate specificity, and inhibition - PubMed
In this mini-review we focus on the de-ubiquitinating enzyme USP7, and summarize latest advances in understanding its structure, substrate specificity and relevance to human cancers. …
USP7 regulates the ERK1/2 signaling pathway through ... - Nature
2022年8月10日 · Ubiquitin-specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUBs) in the ubiquitin-specific protease (USP) family. It is a key regulator of numerous...
泛素特异性肽酶 7（USP7）基因 | MCE - MCE-生物活性分子 ...
该基因编码的蛋白质属于肽酶 C19 家族，其中包括泛素水解酶。 这种蛋白质去泛素化目标蛋白质，如 p53 (一种肿瘤抑制蛋白) 和 WASH (内体蛋白质回收所必需的) ，并通过抵消参与相应过 …
【文献速递501】泛素化及泛素化酶--USP7 - 搜狐
2017年10月24日 · 例如，泛素特异性蛋白酶7（usp7）能够使具有癌基因作用的e3连接酶mdm2降解，并导致肿瘤抑制基因p53在多种癌症中被重新激活。 本文报道了两种化合物FT671 …
USP7: Novel Drug Target in Cancer Therapy - PubMed
2019年4月30日 · Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation. Full activity of …
USP7 ubiquitin specific peptidase 7 [ (human)] - National Center …
USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer. Inhibition of USP7 activity selectively eliminates senescent cells …