Tröger's base and its analogs are soluble in various organic solvents and strong acidic aqueous solutions due to their protonation. It is named after Julius Tröger, who first synthesized it in 1887.

2007年1月1日 · This chapter summarizes Tröger's bases (TBs). It describes its historical developments, revival, synthesis and mechanism of formation, reactivity, physicochemical properties, and its uses and applications. The chapter also provides a …

2012年11月20日 · Tröger's base [TB, (±)- 1] has a unique position in the history of stereochemistry. Since the first use of TB analogues as synthetic receptors less than 30 years ago, interest in the system has exploded thanks to the development of new methods for TB functionalization (virtually all position in the skeleton are now accessible).

2025年2月1日 · In this study, we present Tröger’s base analogs synthesized through condensation between p -formaldehyde and methyl-nitro-anilines in good yields. Tröger’s bases exhibit absorption peaks around 350 nm attributed to allowed ππ* electronic transitions. The fluorescence emission at 380 nm showed no correlation with the position of the nitro group.

2023年2月3日 · Tröger’s Base在自组装研究、分子识别、DNA相互作用的探针以及有机合成中的路易斯碱催化剂等方面的应用而备受关注。 然而，手性的Tröger’s Base很少被大量使用，这是因为它在酸性条件下构型不稳定，限制了其广泛应用。 为此，人们通过修饰裂隙状支架以增加其稳定性，开发了各种具有刚性裂隙状骨架的Tröger’s Base类似物，其中大多数涉及多步合成或后期拆分。 因此，设计合成出更加稳定的Tröger’s Base类似物，并且通过催化不对称合成来实现，已 …

2022年12月1日 · Tröger’s base (TB) and its derivatives have been studied extensively due to their unique concave shape stemming from the endomethylene strap. However, the strap-clipped TB chemistry has been largely overlooked in metal–organic framework (MOF) solids, leading to a gap in our knowledge within this field.

Troger’s Base Troger’s Base 1. Tr 2.TB TB 许多基于这种途径的方法有着最为重要的局限性，就是芳环上的取代基需要有供电子的性质来允许亲电子取代，这代表了形成

Oligo Tröger's bases are compounds containing two or more Tröger's base subunits (1,5-methanodiareno[b,f][1,5]diazocines) sharing one or more arene parts. Due to their interesting molecular shapes, these compounds are studied as chiral molecular tweezers, clips, cavitands, clefts, calixes, etc.

碱催化剂：TROGER碱可作为有机合成中的碱催化剂，参与各种有机反应，如酯化、醚化、硅化等反应。 分子识别：TROGER碱具有刻板相空间的结构，可用于分子识别和酶活性调节。 TROGER碱的制法通常是通过化学合成来实现。 具体方法包括从合适的前体化合物出发，通过一系列反应步骤得到目标产物。 避免与皮肤接触：TROGER碱具有刺激性，接触皮肤可能引起不适和皮肤过敏。 储存注意事项：TROGER碱应储存在干燥、阴凉的地方，远离火源和氧化剂。 …

Troeger's base | C17H18N2 | CID 196981 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...