Functional roles in cell signaling of adaptor protein TRADD …
2020年1月1日 · After activation of specific receptors such as TNFR1 and DR3, TRADD can bind to the receptor through DD-DD interaction, creating a membrane-proximal platform for the …
Structure of the C-terminal domain of TRADD reveals a novel …
2017年8月1日 · Here we present a solution structure of TRADD DD derived from high-resolution NMR spectroscopy. The TRADD DD comprises two super-secondary structures, an all-helix …
死亡受体主导的细胞凋亡 - 知乎 - 知乎专栏
tnf三聚体与tnfr1结合后诱导tnfr1的dd聚集募集衔接蛋白tradd，tradd可募集traf2、rip和fadd等信号分子。 TRAF2和RIP可激活 NF-κB 和JNK/AP信号通路，而FADD可以激活Caspase级联反 …
Redundant and receptor-specific activities of TRADD, RIPK1 …
2019年2月11日 · We evaluated redundant and receptor-specific activities of TRADD, RIPK1, and FADD in RIPK3-expressing HeLa cells lacking expression of these proteins or any …
从结构角度看衔接蛋白TRADD在细胞信号传导中的功能作 …
tradd具有两个不同的功能域，即n末端的traf结合域和c末端的死亡域（dd）。 TRADD的TRAF结合域折叠成α-β褶状拓扑结构，主要负责结合TRAF2，而TRADD-DD可以与多种含DD的蛋白质 …
Roles of the adaptor protein tumor necrosis factor receptor type 1 ...
2022年9月1日 · The C-terminal domain (CTD) of TRADD can specially interact with the intracellular death domain (DD) of tumor necrosis factor receptor 1 (TNFR1), death receptor 3 …
TRADD的C末端结构域的结构揭示了死亡结构域超家族中的新折叠 …
Here we present a solution structure of TRADD DD derived from high-resolution NMR spectroscopy. The TRADD DD comprises two super-secondary structures, an all-helix Greek …
Here we present a solution structure of TRADD DD derived from high-resolution NMR spectroscopy. The TRADD DD comprises two super-secondary structures, an all-helix Greek …
TRADD介导的信号通路及其与疾病的相关性 - wanfangdata.com.cn
2022年11月14日 · 肿瘤坏死因子受体相关死亡结构域蛋白(tumor necrosis factor receptor-associated death domain pro-tein,TRADD)是一种细胞内衔接分子,通过肿瘤坏死因子受 …
5XME: Solution structure of C-terminal domain of TRADD
2017年5月15日 · Here we present a solution structure of TRADD DD derived from high-resolution NMR spectroscopy. The TRADD DD comprises two super-secondary structures, an all-helix …