2023年3月9日 · The total oxidizable precursor (TOP) assay offers a means of bridging this gap by oxidizing unknown PFAS precursors and intermediates and converting them into stable PFASs with established analytical standards.

Here we examine the ability of the TOP assay to identify PFAS sources, including aqueous film-forming foam (AFFF) impacted sites, municipal wastewater treatment plants (WWTPs), and municipal solid waste landfills in 145 samples from 46 locations and three countries.

2024年12月1日 · This review article paves the way for the further implementation of the TOP assay as an important tool to assess the world of PFAS more comprehensively, thereby supporting environmental monitoring, assessment of PFAS contaminations, and the success control of designated PFAS regulations.

2023年5月25日 · Through our own data sources that we’ve been building up during the last decades, as well as report digging, ChemSec is confident in saying that the twelve companies named below are the biggest PFAS producers in the world. Additionally, we have also sized up the corporate profits and the societal costs connected to PFAS.

2024年12月13日 · 总氧化前体物分析（TOP assay）是评估全氟或多氟烷基化合物（PFAS）前体物总量的分析方法，但因基质干扰和超短链PFAS（C<4）检测缺失存在稳定性差和总量被低估等问题，有待进一步优化。

总可氧化前体 (TOP) 测定提供了一种弥补这一差距的方法，即氧化未知的 PFAS 前体和中间体，并将其转化为具有既定分析标准的稳定 PFAS。 将 TOP 测定应用于 PFAS 污染场地的样品产生了一些新的见解，但也给实验室带来了各种技术挑战。 尽管包括 TOP 测定在内的文献研究数量不断增加，但除了学术界研究人员之外，该方法的应用仍存在着关键且不断扩大的差距。 本文概述了使用 TOP 测定法对水样进行现场评估的优点和挑战，并提出了解决其一些局限性的方法。

ECF precursors are transformed into PFCAs of equal chain lengths after oxidation. Barzen-Hanson et al. found that 3M AFFF contains a significant amount of ultrashort PFAS. The ability of the TOP assay to quantify ultrashort precursors will improve the accuracy of estimating the contamination scales during site investigations. Moreover, PFSAs ...

2021年12月15日 · Semi-quantitative test achieved by an app-based smartphone sensor, with help D-LPE to remove background. Total oxidisable precursor assay (TOP assay) can degrade and convert “unknown” per- and polyfluoroalkyl substances (PFAS) to detectable PFAS.

2024年1月20日 · UV-activated TOP assay enables detection of long-chain PFCAs following AFFF oxidation. Inclusion of TFA, PFPrA, FtSaB, and FTB analytical standards improved PFAS quantitation. Per- and polyfluoroalkyl substances (PFAS) encompass over 9000 chemicals utilized in various industrial and commercial applications.

总可氧化前体分析（top 分析）可以将“未知”全氟和多氟烷基物质 (pfas) 降解并转化为可检测的 pfas。 然而，详细的降解途径仍然未知，特别是当 TOP 测定用于分析复杂样品，如水性成膜泡沫 (AFFF) 时。