TMED10 Gene - GeneCards | TMEDA Protein | TMEDA Antibody
2025年3月30日 · TMED10 (Transmembrane P24 Trafficking Protein 10) is a Protein Coding gene. Diseases associated with TMED10 include Alzheimer's Disease and Congenital Disorder Of …
Cell主刊丨TMED10小鼠模型助力蛋白质非经典分泌途径机制阐述
UPS货物中，TMED10 C端与这个motif的相互作用解释了UPS货物的选择性释放。 研究人员进行了体外重组实验表明，TMED10直接介导UPS货物转运进入脂质体内，这依赖于蛋白质的去折 …
TMED10 - Wikipedia
Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene. [4][5][6] This gene is a member of the EMP24/GP25L/p24 family and …
生命学院葛亮课题组在《细胞》发文报道蛋白非经典分泌过程关键 …
2020年4月10日 · 在这项研究中，研究人员鉴定出一个膜蛋白TMED10可能形成一个蛋白通道介导UPS蛋白进入囊泡结构。 细胞实验发现，TMED10能够调控大量非经典分泌蛋白的分泌，包 …
TMED10 mediates the trafficking of insulin-like growth factor 2 …
2023年11月14日 · We found that a type I transmembrane protein, TMED10, is essential for the secretion of IGF2 and for differentiation of mouse myoblast C2C12 cells. Further analyses …
Coronavirus envelope protein activates TMED10-mediated
2024年10月8日 · Here we identify the envelope (E) protein in severe coronaviruses (SARS-CoV-2, SARS, or MERS) as a potent inducer of interleukin-1 release, intensifying lung inflammation …
跨膜 p24 运输蛋白 10（TMED10）基因 - MCE
Ubiquitous expression in thyroid (RPKM 111.9), endometrium (RPKM 61.7) and 25 other tissues. 该基因是 EMP24/GP25L/p24 家族的成员，编码具有 GOLD 结构域的蛋白质。 这种 I 型膜蛋 …
A dual role of ERGIC-localized Rabs in TMED10-mediated ... - Nature
2024年6月26日 · Here we reveal the involvement of ERGIC-localized small GTPases, Rab1 (Rab1A and Rab1B) and Rab2A, in regulating UcPS cargo transport via TMED10 on the ERGIC.
TMED10 transmembrane p24 trafficking protein 10 [ (human)]
2025年2月9日 · The AD-associated protein TMED10 negatively regulates autophagy by inhibiting ATG4B activity. Study validated EXT1, TM9SF2, and TMED10 as important host factors for …
A Translocation Pathway for Vesicle-Mediated Unconventional Protein ...
2020年4月30日 · In an in vitro reconstitution assay, TMED10 directly mediates the membrane translocation of leaderless cargoes into the liposome, which is dependent on protein unfolding …