Streamlight's TLR series gets rechargeable, with the TLR-7® X offering both CR123A and USB-powered options and interchangeable paddle switches.

The TLR-7 X features multi-fuel capability — powered by either one CR123A (included) or one Streamlight SL-B9 lithium-ion rechargeable battery pack (sold separately), both delivering 500 …

Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. [5] It is a member of the toll-like receptor (TLR) family and detects single stranded RNA.

Small and mighty weapon lights that deliver 500 lumens and fit a broad range of full-size and compact handguns. Introducing TLR-8 G with green laser.

2025年3月30日 · TLR7 (Toll Like Receptor 7) is a Protein Coding gene. Diseases associated with TLR7 include Immunodeficiency 74, Covid19-Related, X-Linked and Systemic Lupus Erythematosus 17. Among its related pathways are Toll Like Receptor 7/8 (TLR7/8) Cascade and SARS-CoV-2 Infection.

2017年9月3日 · Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other inflammatory cytokine production is important in antiviral immune responses.

2025年2月9日 · Platelet TLR7 is essential for the formation of platelet-neutrophil complexes and low-density neutrophils in lupus nephritis. Absence of toll-like receptor 7 ameliorates survival and reduces intestinal injury in mice after Clostridium difficile infection.

2022年4月27日 · Here we describe human systemic lupus erythematosus caused by a TLR7 gain-of-function variant. TLR7 is a sensor of viral RNA8,9 and binds to guanosine10–12.

TLR7 is an endosomal sensor that recognizes ssRNA viruses and synthetic oligoribonucleotides (ORN) such as imidazoquinoline, imiquimod, and R-848 [2,14,18]. The ORNs sensed by TLR7 are typically AU rich. TLR7 is primarily, but not only, expressed in hematopoietic cells such as plasmacytoid DCs (pDCs) and B cells [35].

2016年10月18日 · Our structural, biochemical, and mutagenesis studies indicated that TLR7 is a dual receptor for guanosine and uridine-containing ssRNA. Our findings have important implications for understanding of TLR7 function, as well …