TLR3 plays significant roles against hepatitis B virus
2014年1月30日 · This review collected the recent information regarding the important roles of TLR3 in immune responses against HBV and also the status of TLR3 expression and its …
Direct antiviral properties of TLR ligands against HBV ... - Nature
2018年3月29日 · We demonstrated that ligands of TLR1/2 (Pam3CSK4) and TLR3 (poly(I:C)-(HMW) or Riboxxol activated hepatocytes (PHH or dHepaRG) innate responses and efficiently …
TLR3 Plays Significant Roles against HBV-Associated HCC
2015年4月23日 · In the present study, we detected the expression of TLR3 in human HBV-associated HCC tissues and its relation to HBV infection. Furthermore, we stimulated …
Polymorphisms in the Toll-like receptor 3 (TLR3) gene are ... - Nature
2018年8月24日 · Alterations in the TLR3 gene might impair immune responses against HBV. In our study, we analysed the impact of the TLR3 polymorphisms rs3775291 and rs5743305 on …
TLR3 Activation of Hepatic Stellate Cell Line Suppresses HBV ...
2018年12月16日 · We demonstrated that TLR3 signaling of a human stellate cell line (LX-2) could inhibit hepatitis C virus infection of hepatocytes (24). Here, we examined whether LX-2 cells …
Polymorphisms in the Toll-like receptor 3 (TLR3) gene are …
2018年8月24日 · Innate immunity can induce spontaneous hepatitis B surface antigen (HBsAg) seroclearance (SC) of hepatitis B virus (HBV) infection or transition towards an inactive carrier …
Impaired TLR3/IFN-β signaling in monocyte-derived dendritic …
2009年12月18日 · In this study, we demonstrated by linear correlation analysis that TLR3 expression and IFN-β induction in cultured MoDCs were correlated positively with PTA, but …
TLR3在HBV感染诱导的抗病毒免疫中的表达及作用-学位-万方数据 …
摘要： 目的：探讨 TLR3 表达和 TLR3-TBK1-IRF3-IFN-β信号传导通路与乙型肝炎病毒感染后宿主免疫清除障碍的关系. 方法选取HBeAg阳性的慢性乙型肝炎患者58例,健康对照者55例,用免疫 …
Hepatitis B virus genome replication triggers toll-like receptor 3 ...
2016年4月28日 · Our data demonstrate that in the absence of HBsAg, hepatic HBV replication leads to Tlr3-dependent interferon responses in non-parenchymal liver cells. We hypothesize …
Toll-like receptor 3 polymorphism and its association with hepatitis B …
Due to lack of knowledge on the role of TLR3 polymorphisms in HBV infection, this study investigated the distribution of nine SNPs in the TLR3 gene and its association with Saudi …
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